2026-09-24 · 1 篇
约氏乳杆菌N5上清液通过抑制NR4A1-IRE1-XBP1介导的未折叠蛋白反应保护RPMI-2650细胞免受HDM诱导的损伤
Lactobacillus johnsonii N5 Supernatant Protects RPMI-2650 Cells from HDM-Induced Injury in Association with Suppression of the NR4A1-IRE1-XBP1-Mediated Unfolded Protein Response.
2026-09-23 · 2 篇
时间性miRNA重塑界定了间歇性缺氧诱导心肌细胞损伤中免疫炎症激活的24小时调控阈值
Temporal miRNA remodeling defines a 24-hour regulatory threshold for immune-inflammatory activation in intermittent hypoxia-induced cardiomyocyte injury.
一种新型蓝藻血清素N-乙酰转移酶基因CySNAT3的克隆及其与转录组药物重定位在儿童阻塞性睡眠呼吸障碍中的整合
Cloning of a novel cyanobacterial serotonin N-acetyltransferase gene CySNAT3 and its integration with transcriptomic drug repurposing in pediatric obstructive sleep-disordered breathing.
2026-09-21 · 1 篇
臭氧与PM2.5共暴露加重过敏性鼻炎并与PPAR/TRPV1相关屏障损伤有关：来自鼻转录组学和微生物组学的见解。
Ozone and PM2.5 co-exposure exacerbates allergic rhinitis and is associated with PPAR/TRPV1-related barrier damage: Insights from nasal transcriptomics and microbiomics.
2026-09-19 · 4 篇
BCR-NF-κB与IL-4Rα-STAT6信号的合成性共现构成功能性IgE类别转换重组的主检查点
Synthetic coincidence of BCR-NF-κB and IL-4Rα-STAT6 signaling constitutes a master checkpoint for functional IgE class switch recombination.
通过转录组学阐明对橄榄花粉过敏致敏的分子机制。
Elucidating molecular mechanisms of allergic sensitization to olive pollen through transcriptomics.
嗅觉簇细胞对基础炎症、病毒感染先天免疫反应以及静息干细胞活化、增殖和分化的调控至关重要。
Olfactory Tuft Cells Are Critical to Basal Inflammation, Innate Immune Response to Viral Infection, and Modulation of Quiescent Stem Cell Activation, Proliferation and Differentiation.
长读长RNA-seq绘制过敏性鼻炎小鼠模型中三叉神经节的异构体图谱
Long-read RNA-seq maps the isoform landscape of the trigeminal ganglion in an allergic rhinitis mouse model.
2026-09-18 · 2 篇
整合转录组分析揭示过敏性鼻炎患者舌下过敏原免疫治疗相关的基因和细胞
Genes and cells associated with sublingual allergen immunotherapy revealed by integrated transcriptome analysis in allergic rhinitis patients.
嗜酸性慢性鼻窦炎小鼠模型中鼻部微生物群失调与海马神经免疫改变相关
Dysbiosis of nasal microbiota associated with hippocampal neuroimmune alterations in a mouse model of eosinophilic chronic rhinosinusitis.
2026-09-17 · 1 篇
多组学与机器学习鉴定ALOX5为慢性鼻窦炎伴鼻息肉中铁死亡相关上皮屏障功能障碍的驱动因子
Multi-omics and machine learning identify ALOX5 as a ferroptosis-associated driver of epithelial barrier dysfunction in chronic rhinosinusitis with nasal polyps.
2026-09-15 · 3 篇
阻塞性睡眠呼吸暂停综合征（OSAS）中外周单个核细胞的代谢组学：一项关于免疫代谢特征的探索性初步研究。
Peripheral Mononuclear Cells Metabolomics in Obstructive Sleep Apnea Syndrome (OSAS): An Exploratory Pilot Study of Immunometabolic Signatures.
黄芩素通过抑制ALOX15介导的M2巨噬细胞功能减轻嗜酸性鼻窦炎
Baicalein Attenuates Eosinophilic Rhinosinusitis by Suppressing ALOX15-Mediated M2 Macrophage Function.
基于UPLC-QTOF-MS/MS和网络药理学的香菊片血液成分分析
Analysis of Blood Components of Xiangju Tablets Based on UPLC-QTOF-MS/MS and Network Pharmacology.
2026-09-14 · 1 篇
伴与不伴鼻息肉的慢性鼻窦炎患者及健康对照者鼻腔黏液代谢物比较。
Comparison of Nasal Mucus Metabolites in Chronic Rhinosinusitis With and Without Polyps and Healthy Controls.
2026-09-13 · 4 篇
慢性鼻窦炎中PAPP-A表达模式的特征分析
Characterization of PAPP-A Patterns in Chronic Rhinosinusitis.
细胞氧化还原状态与认知衰退中的嗅觉改变相关。
Cellular redox status is linked to olfactory alterations in cognitive decline.
邻苯二甲酸二(2-乙基己基)酯暴露在阻塞性睡眠呼吸暂停中的机制见解：网络毒理学与体外验证
Mechanistic insights into di(2-ethylhexyl) phthalate exposure in obstructive sleep apnea: network toxicology and in vitro validation.
基于计算流体动力学的深部置入鼻腔给药用于精准鼻窦靶向
CFD-Enabled Deep Insert Nasal Delivery for Precision Sinus Targeting.
2026-09-11 · 1 篇
lncRNA DANCR通过抑制miR-338-3p增强过敏性鼻炎的炎症反应
lncRNA DANCR Enhances Inflammatory Response in Allergic Rhinitis by Inhibiting miR-338-3p.