2026-09-11 · 1 篇
小鼠模型中的磷酸化蛋白质组学分析揭示ERK信号是儿童过敏性鼻炎相关鼻黏膜炎症反应的关键调节因子。
Phosphoproteomic analysis in a mouse model reveals ERK signaling as a key modulator of inflammatory response in nasal mucosa associated with childhood allergic rhinitis.
2026-09-10 · 5 篇
HUWE1介导的TTC4泛素化与降解通过抑制PINK1/parkin依赖性线粒体自噬并促进FKBP5/NF-κB诱导的Treg/Th17失衡加重过敏性鼻炎
HUWE1-mediated ubiquitination and degradation of TTC4 aggravates allergic rhinitis via inhibiting PINK1/parkin-dependent mitophagy and promoting FKBP5/NF-κB-induced Treg/Th17 imbalance.
内皮NLRP3细胞焦亡作为慢性间歇性缺氧中血脑屏障破坏和神经毒性星形胶质细胞生成的触发因素
Endothelial NLRP3 pyroptotic as a trigger for blood brain barrier disruption and neurotoxic Astrogenesis in chronic intermittent hypoxia.
CCR3通过IL-33/CD34棕榈酰化在过敏性鼻炎中的作用：一项综合分析
The role of CCR3 via IL-33/CD34 palmitoylation in allergic rhinitis: A comprehensive analysis.
嗅球中TET2缺失加重香烟烟雾诱导的鼻息肉小鼠的嗅觉障碍
TET2 deletion in the olfactory bulb aggravates olfactory impairment in mice with cigarette smoke-induced nasal polyps.
EpCAM适配体修饰的碳@二氧化锰纳米花用于协同药物-纳米酶治疗过敏性鼻炎
EpCAM aptamer modified carbon@manganese dioxide nanoflower for synergistic drug-nanozyme allergic rhinitis treatment.
2026-09-09 · 2 篇
Poly(I:C)激活的鼻成纤维细胞促进CRSwNP中的嗜酸性粒细胞募集
Poly(I:C)-Activated Nasal Fibroblasts Promote Eosinophil Recruitment in CRSwNP.
白三烯受体拮抗剂抑制SLC19A1和SLC46A1介导的叶酸及抗叶酸药物转运
Leukotriene receptor antagonists inhibit SLC19A1 and SLC46A1-mediated transport of folic acid and antifolates.
2026-09-08 · 3 篇
中介素通过AMPK依赖性抑制HIF-1α减轻慢性间歇性缺氧诱导的肾小管上皮细胞代谢重编程并缓解随后的肾纤维化
Intermedin mitigates chronic intermittent hypoxia-induced metabolic reprogramming in tubular epithelial cells and attenuates consequent kidney fibrosis through an AMPK-dependent suppression of HIF-1α.
树枝状聚合物交联的γ-聚谷氨酸/海藻酸钠海绵：增强止血和持续抗炎活性用于鼻窦炎术后治疗
Dendrimer crosslinked γ-polyglutamic acid/sodium alginate sponges: enhanced hemostasis and sustained anti-inflammatory activity for post-sinusitis surgery treatment.
ATP/P2X7信号作为鼻息肉早期复发的潜在预测生物标志物：与炎症小体激活和上皮屏障功能障碍的相关性。
ATP/P2X7 signaling as a potential predictive biomarker for early recurrence of nasal polyps: Correlation with inflammasome activation and epithelial barrier dysfunction.