疑似口腔与生殖器溃疡伴软骨炎（MAGIC）综合征相关重度中心气道狭窄的气道支架置入：一例病例报告

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中文摘要

背景： 口腔与生殖器溃疡伴软骨炎（MAGIC）综合征是白塞病与复发性多软骨炎之间的一种罕见重叠综合征。我们报告一例39岁女性，表现为重度弥漫性中心气道狭窄，尽管反复行支气管镜下扩张及糖皮质激素治疗，仍反复再狭窄。方法：支气管镜检查显示广泛纤维化气道狭窄，活动性炎症轻微，提示不可逆性气道重塑。结果：采用硬质支气管镜置入硅酮Dumon Y型支架，显著改善了呼吸症状、肺功能及气道通畅性。支架于6个月后成功取出，无并发症。结论：因此，气道支架置入可能对疑似MAGIC综合征相关的重度纤维化气道狭窄有效。

英文摘要

Mouth and genital ulcers with inflamed cartilage (MAGIC) syndrome is a rare overlap syndrome between Behçet's disease and relapsing polychondritis. We report the case of a 39-year-old woman with severe diffuse central airway stenosis and recurrent restenosis despite repeated bronchoscopic dilations and corticosteroid therapy. Bronchoscopy revealed extensive fibrotic airway stenosis with minimal active inflammation, suggesting irreversible airway remodeling. A silicone Dumon Y stent was placed using rigid bronchoscopy, which markedly improved the respiratory symptoms, pulmonary function, and airway patency. The stent was successfully removed after 6 months, without complications. Airway stenting may therefore be effective for severe fibrotic airway stenosis associated with suspected MAGIC syndrome.