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内镜鼻窦手术中的类固醇洗脱鼻窦植入物：意大利全国性调查结果

Steroid-eluting sinus implants in endoscopic sinus surgery: results of an Italian Nationwide Survey.

临床研究鼻科IF 2.4Q1

文献信息

PMID42969777
原文在 PubMed 查看原文 ↗
发表日期2026
作者Mario Turri-Zanoni
查看其他 4 位作者

Maurizio Bignami；Marco Ferrari；Piero Nicolai；Fabio Pagella

作者单位Department of Otorhinolaryngology, Ospedale Sant'Anna, ASST Lariana, University of Insubria, Como, Italy.
查看其他 4 条单位信息

Division of Otorhinolaryngology, Department of Surgical Specialties, ASST Sette Laghi, Ospedale di Circolo e Fondazione Macchi, University of Insubria, Varese, Italy.；Section of Otorhinolaryngology - Head and Neck Surgery, Department of Neuroscience, University of Padua, Padua, Italy.；Unit of Otorhinolaryngology - Head and Neck Surgery, Azienda Ospedale-Università Padova, Padua, Italy.；Department of Clinical, Surgical, Diagnostic and Pediatric Sciences, University of Pavia, Pavia, Italy.

期刊Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale
SCI 分区Q1
IF2.4
研究类型临床研究 · 临床
所属专科鼻科

中文摘要

目的： 调查意大利鼻科医生目前关于类固醇洗脱鼻窦植入物（SESIs）的临床实践模式和认知。
方法： 由来自三级转诊中心的5名意大利专家组成的顾问委员会制定了一项关于内镜鼻窦手术（ESS）中SESIs使用的全国性调查，并分发给意大利各地的鼻科外科医生。在145名受邀医生中，103人回复（71%）。3名对SESIs无经验或无兴趣的受访者被排除，最终100名参与者纳入分析。
结果： 在受访者中，46%为SESI使用者，54%为非使用者。SESIs主要用于修正性ESS、额窦手术以及有全身性糖皮质激素禁忌证的患者。使用者认可SESIs在减少再狭窄和促进受控愈合方面的价值。在额窦手术中，SESIs通常被推荐用于修正性病例，尤其是瘢痕相关再狭窄。在筛窦手术中，中鼻甲保留影响了推荐意见。非使用者将高成本、缺乏报销和指南不明确列为主要障碍。
结论： 本调查显示意大利SESI采用情况存在显著差异。尽管在选定病例中其获益得到认可，但经济和指南相关问题限制了更广泛的使用，突出表明需要进行成本效益研究和制定国家指南，以更好地界定SESIs在ESS中的作用。

英文摘要

OBJECTIVE: To investigate current clinical practice patterns and perceptions regarding steroid-eluting sinus implants (SESIs) among Italian rhinologists.
METHODS: A nationwide survey on SESIs use in endoscopic sinus surgery (ESS) was developed by an advisory board of 5 Italian experts from tertiary referral centres and distributed to rhinology surgeons across Italy. Of 145 invited physicians, 103 responded (71%). Three respondents without experience or interest in SESIs were excluded, leaving 100 participants for analysis.
RESULTS: Among respondents, 46% were SESI Users and 54% Non-Users. SESIs were mainly used in revision ESS, frontal sinus surgery, and in patients with contraindications to systemic corticosteroids. Users valued SESIs for reducing restenosis and promoting controlled healing. In frontal sinus surgery, SESIs were commonly recommended in revision cases, especially for scarring-related restenosis. In ethmoid surgery, middle turbinate preservation influenced recommendations. Non-users cited high costs, lack of reimbursement, and limited guideline clarity as the main barriers.
CONCLUSIONS: This survey shows marked variability in SESI adoption in Italy. While benefits are acknowledged in selected cases, economic and guideline-related issues limit wider use, highlighting the need for cost-effectiveness studies and national guidelines to better define the role of SESIs in ESS.