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日本使用长电极进行EAS的结果:一项多中心回顾性调查

Results of EAS performed in Japan using long electrodes: a multicenter retrospective survey.

临床研究耳科IF 1.3Q3

文献信息

中文摘要

背景: 电声刺激(EAS)已成为高频听力损失患者的一种既定治疗选择。在日本,所有FLEX电极于2023年8月获批用于EAS,导致较长电极的使用增加。
目的/目标: 我们调查了该获批对EAS患者选择和电极选择的影响,并比较了较长电极与FLEX24之间的听力保留结果。
材料与方法: 我们回顾性审查了2023年8月至2025年10月在日本27个中心治疗的68例EAS病例(80耳),并将结果与2014年至2016年在20个中心进行的上市后调查中使用FLEX24的55例EAS病例的结果进行了比较。
结果: 两项调查之间的术前听阈和植入时年龄具有可比性。在本次调查中,80耳中有68耳(85%)使用了较长电极(FLEX26、FLEX28或FLEX soft)。植入FLEX28的患者听力保留略差于植入FLEX24的患者;然而,差异无统计学意义。
结论与意义: 即使使用较长电极,也保留了足够的残余听力。这些发现支持越来越多地使用较长电极进行EAS,以提供足够的耳蜗覆盖,同时适应未来听力可能出现的恶化。

英文摘要

BACKGROUND: Electric-acoustic stimulation (EAS) has become an established treatment option for patients with high-frequency hearing loss. In Japan, all FLEX electrodes were approved for EAS in August 2023, resulting in increased use of longer electrodes.
AIMS/OBJECTIVES: We investigated the impact of this approval on patient selection and electrode choice for EAS and compared hearing preservation outcomes between longer electrodes and FLEX24.
MATERIALS AND METHODS: We retrospectively reviewed 68 EAS cases (80 ears) treated at 27 centers in Japan from August 2023 to October 2025 and compared the findings with those from 55 EAS cases using FLEX24 in a post-marketing survey conducted at 20 centers between 2014 and 2016.
RESULTS: Preoperative hearing thresholds and age at implantation were comparable between the two surveys. Longer electrodes (FLEX26, FLEX28, or FLEX soft) were used in 68 of 80 ears (85%) in the present survey. Patients implanted with FLEX28 showed slightly poorer hearing preservation than those implanted with FLEX24; however, the difference was not statistically significant.
CONCLUSIONS AND SIGNIFICANCE: Sufficient residual hearing was preserved even with longer electrodes. These findings support the increasing use of longer electrodes for EAS to provide adequate cochlear coverage while accommodating potential future deterioration in hearing.