头颈癌治疗后10年患者的关切

文献信息

中文摘要

目的： 患者在头颈癌（HNC）诊断和治疗后会经历深刻的功能、心理和社会影响。这些影响可能产生患者希望在治疗后随访咨询中讨论的关切。尽管这些关切在诊断后前五年已有报道，但关于幸存者在更长期报告的关切信息很少。本横断面研究的目的是报告口腔、口咽和喉鳞状细胞癌诊断和治疗10年后患者的关切。
方法： 我们对头颈5000（HN5000）队列的10年随访数据进行了描述性分析，按临床亚组总结患者关切清单（PCI）的应答。
结果： 在5,421名参与者中，2,513人在10年时存活；1,035人返回了问卷，其中661人至少选择了一项PCI关切或一位医疗专业人员。最常见的关切是口干（43%）、吞咽（42%）、害怕复发（33%）、牙齿健康（32%）和咀嚼（29%）。这些关切存在于早期和晚期口腔、口咽、喉部位，尽管观察到细微差异。虽然所有18类多专业人员均被选择，但最常见的两类是牙医（36%）和言语与语言治疗（23%）。
结论： HNC幸存者在治疗后10年报告了广泛的患者优先关切。随着HNC生存率提高，将有越来越多患者带着癌症及其治疗的长期后果生活。因此，医疗资源和支持需要集中于解决患者最关切的问题。

英文摘要

PURPOSE: Patients experience profound functional, psychological and social impacts following head and neck cancer (HNC) diagnosis and treatment. These impacts can generate concerns that patients wish to discuss during post-treatment consultations. Although these concerns have been reported in the first five years after diagnosis, there is little information regarding the concerns reported by survivors in the longer -term. The aim of this cross-sectional study was to report patient concerns 10-years following the diagnosis and treatment of oral cavity, oropharyngeal and laryngeal squamous cell carcinoma.
METHODS: We conducted a descriptive analysis of 10-year follow-up data from the Head and Neck 5000 (HN5000) cohort summarising Patient Concerns Inventory (PCI) responses across clinical subgroups.
RESULTS: Of the 5,421 participants, 2,513 were alive at 10-years; 1,035 returned the questionnaire, with 661 selecting at least one PCI concern or healthcare professional. The most frequent concerns were dry mouth (43%), swallowing (42%), fear of recurrence (33%), dental health (32%), and chewing (29%). These concerns were present across early and late-stage oral, oropharyngeal, laryngeal sites, though subtle differences were observed. Although all 18 multi-professionals were selected, the two most frequent were dentist (36%) and Speech and Language Therapy (23%).
CONCLUSION: A broad range of patient-prioritised concerns were reported by HNC survivors 10 years following treatment. As survival rates in HNC improve there will be an increasing number of patients living with the long-term consequences of cancer and its treatment. Thus, healthcare resources and support need to be focused on addressing those that concern patients most.