前庭性偏头痛患者的听觉时间处理

文献信息

中文摘要

目的： 前庭性偏头痛（VM）与中枢感觉处理异常和神经超兴奋性相关，尽管外周听力正常，这些异常可能破坏时间编码。本研究旨在通过比较VM患者与健康对照者的时间分辨率和时间掩蔽能力，确定VM中听觉时间处理是否受到差异性影响。
方法： 本横断面研究纳入17名年龄20-50岁、患有明确VM的成人以及17名年龄和性别匹配的健康对照者。所有参与者均具有正常听力敏感度和正常认知功能，并经标准化简易精神状态检查（SMMSE）确认。使用间隙检测测试（GDT）和前向掩蔽测试（FMT）评估听觉时间处理。采用适当的统计方法分析组间差异。
结果： 两组在年龄或性别方面未观察到显著差异。与健康对照者相比，VM参与者的GDT表现显著更差，表明听觉时间分辨率受损（p < 0.05）。相反，两组在FMT表现方面未发现显著差异（p > 0.05）。
结论： 尽管外周听力正常，VM个体表现出听觉时间处理的选择性损害。这些发现支持将中枢听觉时间处理评估纳入该人群的全面听力学评估，并提示针对时间处理缺陷的听觉训练可能成为未来康复的潜在途径。

英文摘要

OBJECTIVE: Vestibular migraine (VM) has been associated with central sensory processing abnormalities and neural hyperexcitability, which may disrupt temporal coding despite normal peripheral hearing. This study aimed to determine whether auditory temporal processing is differentially affected in VM by comparing temporal resolution and temporal masking abilities with those of healthy controls.
METHODS: This cross-sectional study included 17 adults aged 20-50 years with definite VM and 17 age- and sex-matched healthy controls. All participants had normal hearing sensitivity and normal cognitive function, confirmed using the Standardized Mini-Mental State Examination (SMMSE). Auditory temporal processing was evaluated using the Gap Detection Test (GDT) and the Forward Masking Test (FMT). Group differences were analyzed using appropriate statistical methods.
RESULTS: No significant differences were observed between the groups regarding age or sex. Participants with VM demonstrated significantly poorer GDT performance compared with healthy controls, indicating impaired auditory temporal resolution (p < 0.05). In contrast, no significant difference was found between the groups in FMT performance (p > 0.05).
CONCLUSIONS: Individuals with VM exhibit selective impairment of auditory temporal processing despite normal peripheral hearing. These findings support the inclusion of central auditory temporal processing assessment as part of the comprehensive audiological evaluation of this population and suggest that auditory training targeting temporal processing deficits may represent a potential avenue for future rehabilitation.