听力损失对视觉选择性注意的影响：来自N2pc与静息态网络的证据
Impact of hearing loss on visual selective attention: Evidence from N2pc and resting-state networks.
文献信息
| PMID | 42951224 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Tongao Zeng |
| 作者单位 | School of Education Science, Hunan Normal University, Changsha, China; Department of Special Education, Faculty of Education, East China Normal University, Shanghai, China; Tibet Autonomous Region Key Laboratory for High Altitude Brain Science and Environmental Acclimatization, Tibet University, Lhasa, China. |
| 期刊 | NeuroImage |
| SCI 分区 | Q1 |
| IF | 6.6 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
背景： 高效的视觉注意是环境适应与社会互动的基础。既往研究虽已观察到聋人个体视觉加工的改变，但这些改变究竟源于听力损失（感觉补偿 vs. 认知缺陷）还是手语经验，研究结果仍存在争议。为解决这一问题，本研究提供任务相关与静息态脑电图（EEG）证据，以厘清视觉选择性注意可塑性的具体驱动因素。方法：采用视觉搜索任务考察95名参与者的选择性注意（34名语前聋者、27名听力正常手语者、34名听力正常非手语者）。结果：与两个听力正常组相比，聋人个体的击中率显著更低，N2后部对侧（N2pc）波幅显著减弱。听力正常手语者与非手语者在行为表现、N2pc波幅及静息态网络拓扑上表现相当，而聋人组进一步表现为静息态alpha网络拓扑退化，证据为聚类系数、全局效率降低以及额-枕连接减弱。N2pc波幅与静息态网络属性及行为正确率显著相关。结论：这些结果提示，聋人个体可能存在视觉选择性注意调节失衡，其最清晰的指标为诱发性N2pc及内在alpha网络组织，且可能与听觉监测丧失后资源竞争增加有关。我们的发现提供了神经生理学证据，表明这些注意缺陷与听力损失相关，而非与手语经验相关，为理解人脑跨模态可塑性的边界提供了新视角。
英文摘要
Efficient visual attention is fundamental to environmental adaptation and social interaction. While previous studies have observed alterations in visual processing among deaf individuals, findings remain controversial regarding whether these changes stem from hearing loss (sensory compensation vs. cognitive deficit) or sign language experience. To address this issue, the present study provides task-related and resting-state electroencephalography (EEG) evidence to disentangle the specific drivers of visual selective attention plasticity. A visual search task was used to examine selective attention in 95 participants (34 prelingual deaf, 27 hearing signers, and 34 hearing nonsigners). Compared to both hearing groups, deaf individuals exhibited significantly lower hit rates and diminished N2-posterior contralateral (N2pc) amplitudes. Hearing signers and nonsigners showed comparable behavioral performance, N2pc amplitudes, and resting-state network topology, whereas the deaf group was further characterized by a degraded resting-state alpha network topology, evidenced by reduced clustering coefficients, global efficiency, and weakened frontal-occipital connectivity. N2pc amplitude correlated significantly with resting-state network properties and behavioral accuracy. These results suggest that deaf individuals may suffer from an imbalance in the regulation of visual selective attention, most clearly indexed by the evoked N2pc and by intrinsic alpha-network organization, and likely linked to increased resource competition following the loss of auditory monitoring. Our findings provide neurophysiological evidence that these attentional deficits are associated with hearing loss rather than with sign-language experience, offering a new perspective for understanding the boundaries of cross-modal plasticity in the human brain.