在数字化赋能代谢照护模式下管理的代谢人群的心理社会与症状负担：一项真实世界横断面研究
Psychosocial and symptom burden across metabolic populations managed in a digitally enabled metabolic care model: a real-world cross-sectional study.
文献信息
| PMID | 42946059 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Hala Zakaria |
| 作者单位 | Metabolic (GluCare.Health), Dubai, United Arab Emirates. Electronic address: hala@metabolic.health. |
| 期刊 | Diabetes research and clinical practice |
| SCI 分区 | Q2 |
| IF | 6.2 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 鼻科 |
中文摘要
背景： 心理社会筛查在糖尿病照护中日益增多，但其在更广泛代谢人群中的作用仍不明确。本研究旨在描述通过数字化赋能的混合照护模式管理的个体中患者报告的心理社会结局及其与心血管代谢特征的关联。
方法： 这项回顾性横断面研究纳入2024年9月至2025年12月期间在Metabolic（阿拉伯联合酋长国）入组的成人。患者被分为糖尿病（DM）、非糖尿病代谢（NDM）和超重-肥胖重点（OB）队列。各种心理社会工具的评分根据条目级应答重新计算，生化指标从病历中提取。采用多变量logistic回归检验关联。
结果： 在7,449例患者中，937例（12.6%）为DM，5,594例（75.1%）为NDM，918例（12.3%）为OB。阻塞性睡眠呼吸暂停高风险在DM中占49.8%，NDM中占27.7%，OB中占32.4%。抑郁症状在DM（25.6%）和NDM（23.5%）中报告率相似；焦虑症状在各组间也相当。糖尿病痛苦影响50.6%的DM患者。HbA1c与PAID-5痛苦相关，BMI与多种心理社会结局相关；区分度中等（AUC 0.55-0.67）。结论：抑郁和焦虑症状在非糖尿病和糖尿病患者中均普遍存在，提示需要在糖尿病之外进行结构化筛查。
英文摘要
BACKGROUND: Psychosocial screening is growing in diabetes care, however, its role in broader metabolic populations remains unclear. This study aimed to describe patient-reported psychosocial outcomes and their associations with cardiometabolic characteristics in individuals managed through a digitally enabled hybrid care model.
METHODS: This retrospective cross-sectional study included adults at Metabolic (United Arab Emirates) enrolled between September 2024 and December 2025. Patients were categorized into diabetic (DM), non-diabetic metabolic (NDM), and overweight-obesity focused (OB) cohorts. Scores for various psychosocial tools were recomputed from item-level responses, and biochemical measures were extracted from medical records. Associations were examined with multivariable logistic regression.
RESULTS: Of 7,449 patients, 937 (12.6%) had DM, 5,594 (75.1%) had NDM, and 918 (12.3%) had OB. High risk for obstructive sleep apnea was present in 49.8% of DM, 27.7% of NDM, and 32.4% of OB patients. Depressive symptoms were reported similarly in DM (25.6%) and NDM (23.5%); anxiety symptoms were also comparable across groups. Diabetes distress affected 50.6% of DM patients. HbA1c correlated with PAID-5 distress, and BMI was associated with various psychosocial outcomes; discrimination was modest (AUC 0.55-0.67). Conclusion Depressive and anxiety symptoms were prevalent in both non-diabetic and those with diabetes, suggesting the need for structured screening beyond diabetes.