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2005至2019年罗宾斯空军基地纯音测听听力变化与耳毒性金属和溶剂、连续噪声及脉冲噪声暴露的回顾性队列研究

Retrospective cohort study of pure tone audiometry hearing changes from ototoxic metals and solvents, continuous noise and impulse noise exposures at Robins Air Force Base from 2005 to 2019.

临床研究耳科IF 2.4Q3

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中文摘要

一项针对罗宾斯空军基地(RAFB)人员的连续噪声、脉冲噪声、重金属和溶剂暴露与纯音测听数据的回顾性研究,使用来自希尔空军基地研究的仅噪声对照组,调查了听力损失的相对风险(RR)。连续噪声+脉冲噪声+重金属在500 Hz左耳(RR=4.90,95% CI:1.81-13.25)和1,000 Hz左耳(RR=4.45,95% CI:1.41-14.10)存在显著RR;连续噪声+脉冲噪声在1,000 Hz左耳(RR=2.77,95% CI:1.06-7.24)也存在显著RR。相反,连续噪声+脉冲噪声在4,000 Hz左耳(RR=0.51,95% CI:0.35-0.74)和右耳(RR=0.68,95% CI:0.46-0.99)显示出保护效应,连续噪声+脉冲噪声+耳毒性溶剂在左耳(RR=0.38,95% CI:0.17-0.86)也显示出保护效应。

英文摘要

A retrospective study of continuous noise, impulse noise, heavy metals, and solvent exposure and pure-tone audiometry data on Robins AFB (RAFB) personnel investigated the relative risk (RR) of hearing loss, using a noise-only control group from a Hill AFB study. There were significant RRs for continuous noise + impulse noise + heavy metals (RR = 4.90, 95% CI: 1.81-13.25, 500 Hz, left ear; RR = 4.45, 95% CI: 1.41-14.10, 1,000 Hz, left ear), and continuous noise + impulse noise (RR = 2.77, 95% CI: 1.06-7.24, 1,000 Hz, left ear). Conversely, there was a protective effect at 4,000 Hz for continuous noise + impulse noise (RR = 0.51, 95% CI: 0.35 - 0.74, left ear; RR = 0.68, 95% CI: 0.46-0.99, right ear) and continuous noise + impulse noise + ototoxic solvents (RR = 0.38, 95% CI: 0.17-0.86, left ear).