获得性单侧耳聋——患者更倾向于侵入性而非非侵入性听力解决方案：一项系统综述与荟萃分析
Acquired Single-Sided Deafness - Patients Prefer Invasive over Non-Invasive Hearing Solutions: A Systematic Review and Meta-analysis.
文献信息
| PMID | 42929386 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Melissa Lee |
| 作者单位 | Department of Otolaryngology-Head and Neck Surgery, University of Toronto Temerty Faculty of Medicine, Canada. |
| 期刊 | The Journal of laryngology and otology |
| SCI 分区 | Q3 |
| IF | 1.1 |
| 研究类型 | 综述 Meta · 临床 |
| 所属专科 | 耳科 |
中文摘要
目的： 比较植入式与非植入式听力解决方案对获得性单侧耳聋成人主观听力残疾及健康相关生活质量的有效性。
方法： 本系统综述遵循系统综述与荟萃分析优先报告条目2020指南，并在系统综述前瞻性注册库中注册。检索多个数据库自1965年1月至2025年10月，纳入报告人工耳蜗、骨传导装置及对侧信号路由助听器作为单侧耳聋治疗的患者报告听力残疾和健康相关生活质量效用测量的研究。
结果： 对13项研究（403名参与者）的汇总分析显示，与无干预相比，植入式解决方案改善了听力残疾评分[均数差 = -14.71（95% CI：-23.48，-5.93），p < 0.00001]。非植入式骨传导装置显示的听力残疾低于对侧信号路由助听器[均数差 = 4.70（95% CI：0.27，9.14）；p = 0.04]。与无听力解决方案相比，人工耳蜗显著改善了健康相关生活质量[均数差 = 0.21（95% CI：0.10，0.31）；p = 0.0001]。
结论： 单侧耳聋患者报告，植入式听力解决方案的平均听力相关改善大于非植入式听力解决方案。
英文摘要
OBJECTIVE: To compare the effectiveness of implanted and non-implanted hearing solutions on subjective hearing disability and health-related quality of life in adults with acquired single-sided deafness.
METHODS: This systematic review adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guidelines and was registered in the Prospective Register of Systematic Reviews. Multiple databases were searched from January 1965 to October 2025 for studies reporting patient-reported hearing disability and health-related quality of life utility measures with cochlear implants, bone-conduction devices and contralateral routing of signal hearing aids as single-sided deafness treatments.
RESULTS: Pooled analysis of 13 studies (403 participants) demonstrated improved hearing disability scores with implanted solutions compared with no intervention [mean difference = -14.71 (95% CI: -23.48, -5.93), p < 0.00001]. Non-implanted bone-conduction devices demonstrated lower hearing disability than contralateral routing of signal aids [mean difference = 4.70 (95% CI: 0.27, 9.14); p = 0.04]. Cochlear implants significantly improved health-related quality of life compared with no hearing solution [mean difference = 0.21 (95% CI: 0.10, 0.31); p = 0.0001].
CONCLUSION: Single-sided deafness patients reported greater mean hearing-related improvement with implanted than non-implanted hearing solutions.