社区居住老年人高频听力阈值与肌少症之间的性别特异性关联
Sex-specific Association Between High-frequency Hearing Thresholds and Sarcopenia in Community-dwelling Older Adults.
文献信息
| PMID | 42907388 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Shinta Yamamoto |
| 作者单位 | Department of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Japan. |
| 期刊 | Internal medicine (Tokyo, Japan) |
| SCI 分区 | Q3 |
| IF | 1 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
目的： 探讨老年人听力阈值与肌少症之间的关联，以及包括肌肉量、肌肉力量和身体功能在内的相关因素。
患者或材料： 参加京丹后长寿队列研究的≥65岁社区居住成年人。
方法： 进行横断面分析。使用听力计测量1,000 Hz和4,000 Hz的听力阈值。根据亚洲肌少症工作组定义的标准诊断肌少症。使用logistic回归模型评估听力阈值与肌少症及其各组成部分之间的关联，并校正潜在混杂变量。
结果： 共分析1,032名参与者（415名男性），平均年龄73.6岁。1,000 Hz的平均（SD）听力阈值为31.3（17.2）dB，4,000 Hz为43.6（20.8）dB。7%的参与者存在肌少症（男性7%，女性6%）。在男性中，4,000 Hz阈值较高（听力较差）与肌少症发生几率增加显著相关（OR = 1.22，95% CI：1.08-1.37，p = 0.001），而女性中未观察到关联（交互作用p = 0.007）。在男性中，重度听力损失（4,000 Hz ≥60 dB）与肌少症可能性较高相关（OR = 3.46，95% CI：1.31-9.13，交互作用p = 0.02）。
结论： 高频听力较差与老年男性肌少症显著相关，但与女性无关。这些结果提示，老年人高频听力损失与肌少症之间存在性别特异性关联。
英文摘要
Objective To investigate the association between hearing thresholds and sarcopenia, as well as related factors, including muscle mass, muscle strength, and the physical function, among older adults.Patients or Materials Community-dwelling adults ≥65 years of age who participated in the Kyotango Longevity Cohort Study.Methods A cross-sectional analysis was performed. Hearing thresholds at 1,000 and 4,000 Hz were measured using an audiometer. Sarcopenia was diagnosed based on the criteria defined by the Asian Working Group for Sarcopenia. Logistic regression models were used to assess the association between hearing thresholds and sarcopenia and its components, adjusting for potential confounding variables.Results A total of 1,032 participants (415 males) with a mean age of 73.6 years were analyzed. The mean (SD) hearing thresholds were 31.3 (17.2) dB at 1,000 Hz and 43.6 (20.8) dB at 4,000 Hz. Sarcopenia was present in 7% of the participants (7% of men and 6% of women). In males, higher thresholds (worse hearing) at 4000 Hz were significantly associated with increased odds of sarcopenia (OR = 1.22, 95% CI: 1.08-1.37, p = 0.001), whereas no association was observed in females ( p for interaction = 0.007). In men, severe hearing loss (≥60 dB at 4000 Hz) was associated with a greater likelihood of sarcopenia (OR = 3.46, 95% CI: 1.31-9.13, p for interaction = 0.02).Conclusion Poor hearing at high frequencies was significantly associated with sarcopenia in older men but not in women. These results suggest a sex-specific association between high-frequency hearing loss and sarcopenia in older adults.