Article record

从多囊卵巢综合征到多内分泌代谢性卵巢综合征：实用临床综述

From Polycystic Ovary Syndrome to Polyendocrine Metabolic Ovarian Syndrome: A Practical Clinical Review.

综述 Meta鼻科IF 2.5Q2

文献信息

PMID	42906749
原文	在 PubMed 查看原文 ↗
发表日期	2026
作者	Licy L Yanes Cardozo 查看其他 4 位作者 Manar A Eissa；Jelina Basnet；Katie Thompson；Damian G Romero
作者单位	Departments of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS; Departments of Medicine (Endocrinology), University of Mississippi Medical Center, Jackson, MS; Departments of Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson, MS; Departments of Women's Health Research Center, University of Mississippi Medical Center, Jackson, MS; Departments of Cardiovascular Renal Research Center, University of Mississippi Medical Center, Jackson, MS. Electronic address: lyanes@umc.edu. 查看其他 3 条单位信息 Departments of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS; Departments of Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson, MS; Departments of Women's Health Research Center, University of Mississippi Medical Center, Jackson, MS; Departments of Cardiovascular Renal Research Center, University of Mississippi Medical Center, Jackson, MS.；Departments of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS; Departments of Cell and Molecular Biology, University of Mississippi Medical Center, Jackson, MS; Departments of Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson, MS; Departments of Women's Health Research Center, University of Mississippi Medical Center, Jackson, MS; Departments of Cardiovascular Renal Research Center, University of Mississippi Medical Center, Jackson, MS.；Departments of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson, MS; Departments of Mississippi Center of Excellence in Perinatal Research, University of Mississippi Medical Center, Jackson, MS; Departments of Women's Health Research Center, University of Mississippi Medical Center, Jackson, MS; Departments of Cardiovascular Renal Research Center, University of Mississippi Medical Center, Jackson, MS. Electronic address: dromero@umc.edu.
期刊	The American journal of the medical sciences
SCI 分区	Q2
IF	2.5
研究类型	综述 Meta · 临床
所属专科	鼻科

中文摘要

多囊卵巢综合征（PCOS）近期被重新命名为多内分泌代谢性卵巢综合征（PMOS），是影响育龄女性最常见的 endocrine 疾病。新命名反映了人们日益认识到该病症远不止卵巢功能障碍，还涵盖复杂的内分泌、代谢、心血管和心理异常。尽管诊断标准保持不变，但名称变更强调了该疾病的多系统性质，并可能改善疾病识别和患者照护。本综述基于证据，对 PMOS/PCOS 的诊断和管理提供实用概述，重点介绍 2023 年国际循证指南的最新更新。我们讨论育龄女性高雄激素血症和排卵功能障碍的评估，以及肥胖、胰岛素抵抗、2 型糖尿病、高血压、血脂异常、代谢功能障碍相关脂肪性肝病、阻塞性睡眠呼吸暂停和心理健康障碍的评估与治疗。最后，我们总结当前药物治疗和新兴治疗策略，并强调为优化长期心脏代谢和生殖结局必须弥合的关键知识空白。

英文摘要

Polycystic Ovary Syndrome (PCOS), recently renamed Polyendocrine Metabolic Ovarian Syndrome (PMOS), is the most common endocrine disorder affecting women of reproductive age. The new nomenclature reflects growing recognition that this condition extends far beyond ovarian dysfunction, encompassing complex endocrine, metabolic, cardiovascular, and psychological abnormalities. Although the diagnostic criteria remain unchanged, the name change emphasizes the multisystem nature of the disorder and may improve disease recognition and patient care. This review provides a practical, evidence-based overview of the diagnosis and management of PMOS/PCOS, highlighting recent updates from the 2023 International Evidence-Based Guideline. We discuss the evaluation of hyperandrogenism and ovulatory dysfunction in reproductive-aged women, as well as the assessment and treatment of obesity, insulin resistance, type 2 diabetes mellitus, hypertension, dyslipidemia, metabolic dysfunction-associated steatotic liver disease, obstructive sleep apnea, and mental health disorders. Finally, we summarize current pharmacological therapies and emerging treatment strategies, highlighting key knowledge gaps that must be bridged to optimize long-term cardiometabolic and reproductive outcomes.