脑干听觉诱发电位在颅脑损伤后吞咽困难诊断评估中的价值

文献信息

中文摘要

目的： 本研究旨在探讨脑干听觉诱发电位在颅脑损伤后吞咽困难诊断评估中的价值。
方法： 为探讨脑干听觉诱发电位（BAEPs）在吞咽困难诊断中的作用，我们前瞻性分析了106例颅脑损伤患者的BAEP结果与金标准诊断。纳入标准：①年龄18-70岁；②根据《中国吞咽障碍评估与治疗专家共识》诊断。排除标准：①格拉斯哥昏迷评分≤8分且无法进行干预管理的患者；②既往可能影响吞咽功能的合并症。
结果： 共纳入65例男性和41例女性患者。BAEP在中重度吞咽困难中的阳性率为86.96%，显著高于轻度吞咽困难组（45.95%；p < 0.01）。60例患者为BAEP阳性且为中重度吞咽困难患者，被认为是神经源性吞咽困难；46例患者为BAEP阴性，被认为是非神经源性吞咽困难。BAEP诊断中重度吞咽困难的AUC为0.705。
结论： BAEP可作为神经损伤的准确诊断方法，有助于鉴别是否为神经源性吞咽困难。

英文摘要

PURPOSE: The aim of this study was to explore the value of brainstem auditory evoked potentials in the diagnostic assessment of dysphagia after craniocerebral injury.
METHODS: To investigate the role of brainstem auditory evoked potentials (BAEPs) in dysphagia diagnosis, we prospectively analyzed BAEP findings and gold-standard diagnoses in 106 patients with head injury. Inclusion criteria: ① Age 18-70 years old; ② Diagnosed by Chinese Expert Consensus on Evaluation and Treatment of Dysphagia. Exclusion criteria: ① Patients with a Glasgow coma scale score ≤8 and patients who cannot be managed with intervention; ② Previous comorbidities that may affect swallowing function.
RESULTS: A total of 65 males and 41 females patients were enrolled. The positive rate of BAEP in moderate to severe dysphagia was 86.96%, which was significantly higher than that in the mild dysphagia group (45.95%; p < 0.01). 60 patients were BAEP-positive and moderate-to-severe dysphagia patients, and considered neurogenic dysphagia, 46 patients were BAEP-negative, and considered non-neurophagia. The AUC of BAEP diagnosis of moderate to severe dysphagia was 0.705.
CONCLUSION: BAEP can be used as an accurate diagnostic method for nerve injury, it is helpful to identify whether it is a neurological dysphagia.