上气道激光年轻化：一种治疗习惯性打鼾的新型非手术方法
Laser-Based Rejuvenation of the Upper Airway: A Novel Non-Surgical Approach to Habitual Snoring.
文献信息
| PMID | 42892924 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Rohit Kothari |
| 作者单位 | Department of Dermatology, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, India. |
| 期刊 | Journal of lasers in medical sciences |
| SCI 分区 | Q3 |
| IF | 1.9 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
引言： 本研究旨在评估掺铒钇铝石榴石（Er:YAG，2940 nm）联合长脉冲Nd:YAG激光在减轻习惯性打鼾方面的疗效。
方法： 三十例患者参与这项单臂前瞻性研究，使用PSO3X手柄在长脉冲（LP）模式下以图案化光束将约20,000个Er:YAG激光脉冲导向目标部位，随后对颏下及侧颈部区域进行长脉冲Nd:YAG照射。治疗分别在第0、15和45天实施。治疗反应通过主观方法评估，包括打鼾结局调查（SOS）和配偶/床伴调查（SBPS）。解剖学改善在每次治疗前及末次治疗九个月后使用Mallampati分级进行评估。
结果： 平均Mallampati分级从3.50±0.68降至2.43±0.73。SOS和SBPS评分观察到具有统计学意义的改变，分别从47.10±11.34升至66.22±11.18，以及从44.38±16.22升至63.11±14.64。年龄较大与Mallampati分级呈临界相关，而体重和BMI则无相关性；基线SOS评分较低的患者倾向于改善更多。
结论： 在这项单臂初步研究中，Er:YAG与Nd:YAG联合方案耐受性良好，并与习惯性打鼾的改善相关；需要对照试验来确认其在打鼾早期管理中的疗效。
英文摘要
Introduction: This study aimed to evaluate the efficacy of Erbium-Doped Yttrium Aluminium Garnet (Er: YAG, 2940 nm), combined with a long-pulse Nd: YAG laser, in mitigating habitual snoring. Methods: Thirty patients participated in the single-arm prospective study, receiving approximately 20,000 pulses of the Er: YAG laser directed at the target sites using a patterned beam from the PSO3X handpiece in Long Pulse (LP) mode, followed by long-pulse Nd: YAG irradiation of the submental and lateral neck region. Treatments were administered on days 0, 15, and 45. The treatment response was evaluated through subjective methods, including the Snore Outcomes Survey (SOS) and the Spouse/Bed Partner Survey (SBPS). Anatomical enhancement was assessed using the Mallampati classification before each session and nine months subsequent to the final session. Results: The mean Mallampati class decreased from 3.50±0.68 to 2.43±0.73. Statistically significant alterations were observed in the SOS and SBPS scores, which increased from 47.10±11.34 to 66.22±11.18 and from 44.38±16.22 to 63.11±14.64, respectively. Older age showed a borderline correlation with the Mallampati class, whereas weight and BMI did not; patients with lower baseline SOS scores tended to improve more. Conclusion: In this single-arm pilot study, the combined Er: YAG and Nd: YAG protocol was well tolerated and was associated with improvements in habitual snoring; controlled trials are required to confirm its efficacy in the early management of snoring.