嗓音训练与吞咽功能锻炼对喉癌患者术后功能恢复的长期影响：一项回顾性队列研究
Long-term effects of voice training and swallowing function exercises on postoperative functional recovery in laryngeal cancer patients: a retrospective cohort study.
文献信息
| PMID | 42886344 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Jing Liu |
| 作者单位 | Department of Gynecology, Shanxi Province Cancer Hospital, Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences, Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan City, Shanxi Province, 030013, China. |
| 期刊 | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer |
| SCI 分区 | Q1 |
| IF | 3.7 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
目的： 探讨嗓音训练联合吞咽功能锻炼对喉癌术后患者功能恢复、生活质量及并发症的长期影响。
方法： 在这项回顾性队列研究中，将2019年6月至2023年6月期间接受喉癌手术的120例患者分为康复组（n=60，接受系统性嗓音与吞咽训练）和常规护理组（n=60）。采用嗓音障碍指数（VHI）、吞咽功能量表（SFS）和EQ-5D在术后6、12和24个月评估结局。同时记录并发症。
结果： 术后12个月时，康复组显示出显著优于常规护理组的结局：VHI评分更低（35.25±5.12 vs. 58.70±6.84，P<0.001）、吞咽困难发生率更低（10.00% vs. 30.00%，P=0.008）、EQ-5D指数更高（0.82±0.09 vs. 0.68±0.11，P<0.001）、总并发症发生率更低（11.67% vs. 26.67%，P=0.032）、满意度评分更高（87.80±7.93 vs. 72.21±9.22，P<0.001）。多因素分析证实综合康复是嗓音功能（β=-9.215，P<0.001）、吞咽功能（β=-3.268，P<0.001）及并发症减少（OR=0.218，P<0.001）的独立保护因素。
结论： 系统性嗓音与吞咽联合康复训练可有效促进喉癌患者的功能恢复，显著改善长期生活质量，并降低术后并发症风险。
英文摘要
OBJECTIVE: To investigate the long-term effects of combined voice training and swallowing function exercises on functional recovery, quality of life, and complications in patients after laryngeal cancer surgery.
METHODS: In this retrospective cohort study, 120 patients who underwent laryngeal cancer surgery between June 2019 and June 2023 were divided into a rehabilitation group (n = 60, receiving systematic voice and swallowing training) and a routine care group (n = 60). Voice Handicap Index (VHI), Swallowing Function Scale (SFS), and EQ-5D were used to assess outcomes at 6, 12, and 24 months postoperatively. Complications were also recorded. RESULTS : At 12 months postoperatively, the rehabilitation group showed significantly better outcomes than the routine care group: lower VHI score (35.25 ± 5.12 vs. 58.70 ± 6.84, P < 0.001), lower dysphagia incidence (10.00% vs. 30.00%, P = 0.008), higher EQ-5D index (0.82 ± 0.09 vs. 0.68 ± 0.11, P < 0.001), lower total complication rate (11.67% vs. 26.67%, P = 0.032), and higher satisfaction score (87.80 ± 7.93 vs. 72.21 ± 9.22, P < 0.001). Multivariate analysis confirmed comprehensive rehabilitation as an independent protective factor for voice function (β = -9.215, P < 0.001), swallowing function (β = -3.268, P < 0.001), and complication reduction (OR = 0.218, P < 0.001).
CONCLUSION: Systematic combined voice and swallowing rehabilitation training can effectively promote functional recovery, significantly improve long-term quality of life, and reduce the risk of postoperative complications in laryngeal cancer patients.