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健康人群中丸剂吞咽困难者的舌骨上肌厚度、吞咽焦虑与饮水吞咽表现评估:一项横断面研究

Evaluation of Suprahyoid Muscle Thickness, Swallowing Anxiety, and Water-Swallowing Performance in Healthy People with Pill Dysphagia: A Cross-Sectional Study.

临床研究咽喉科IF 3.3Q1

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中文摘要

背景: 丸剂吞咽困难(PD)是影响健康个体的严重问题,可导致用药依从性差和潜在健康风险。舌骨上肌厚度与吞咽表现之间的关系在PD中仍未充分探讨。本研究旨在评估健康PD个体的吞咽焦虑、伴丸剂饮水吞咽表现以及舌骨上肌厚度。
方法: 在有和无PD的健康个体中评估吞咽焦虑、伴丸剂饮水吞咽表现、B超肌肉厚度以及吞咽丸剂时感受到的困难程度。
结果: 研究纳入20名PD受试者(PD组)和20名无PD受试者(对照组),包括27名男性和13名女性,平均年龄23.98 ± 2.97岁(18-32岁)。对照组二腹肌前腹、下颌舌骨肌和颏舌骨肌的厚度值大于PD组(分别为p < 0.000、p < 0.000、p:0.007)。PD组吞咽困难严重程度、吞咽焦虑以及吞咽丸剂时经历的困难程度更高(分别为p:0.001、p:0.001、p < 0.000)。对照组在有/无丸剂时的饮水吞咽速度和容量更好(分别为p < 0.000;p < 0.000;p:0.005;p < 0.000)。两组在有和无丸剂时吞咽的水量无差异(分别为p:0.468、p:0.162)。
结论: 在伴有丸剂吞咽困难的健康个体中,舌骨上(SH)肌厚度减少可能与丸剂吞咽困难相关。需要随机对照试验研究SH肌锻炼对伴有吞咽困难健康个体的效果。

英文摘要

BACKGROUND: Pill dysphagia (PD) is a serious problem affecting healthy individuals, leading to poor medication adherence and potential health risks. The relationship between suprahyoid muscle thickness and swallowing performance remains underexplored in PD. This study aimed to evaluate swallowing anxiety, water-swallowing performance with pills, and the thickness of the suprahyoid muscles of healthy individuals with PD.
METHODS: Swallowing anxiety, water-swallowing performance with pills, muscle thickness on B-ultrasound, and the level of difficulty felt during pill swallowing were evaluated in healthy individuals with and without PD.
RESULTS: The study included 20 subjects with PD (PD group) and 20 subjects without PD (control group), comprising 27 males and 13 females with a mean age of 23.98 ± 2.97 years (18-32 years). The thickness values of the anterior venter of the digastric muscle, the mylohyoid, and geniohyoid muscles were greater in the control group than in the PD group (p < 0.000, p < 0.000, p:0.007, respectively). The severity of swallowing difficulty, swallowing anxiety, and the degree of difficulty experienced when swallowing pills were determined to be higher in the PD group (p:0.001, p:0.001, p < 0.000, respectively). Water-swallowing speed and capacity with/without pills were better in the control group (p < 0.000; p < 0.000; p:0.005; p < 0.000, respectively). No difference was observed between the groups in the volume of water swallowed with and without pills (p:0.468, p:0.162, respectively).
CONCLUSIONS: In healthy individuals with pill dysphagia, a reduction in the thickness of the suprahyoid (SH) muscles may be associated with pill dysphagia. Randomized controlled trials investigating the effects of SH muscle exercises in healthy individuals with dysphagia are needed.