咀嚼功能与上颌缺损患者确定性阻塞器修复后的生活质量相关。

文献信息

中文摘要

背景： 本横断面研究旨在探讨上颌缺损患者在接受确定性阻塞器修复后，客观评估的口腔功能与生活质量（QoL）之间的关联。方法：研究参与者为67例在上颌骨切除术后完成确定性阻塞器修复的假体康复患者。咀嚼功能、咬合力和舌压作为口腔功能的客观指标进行评估。临床变量包括性别、年龄、手术及假体修复后的时间、缺损范围、放疗史和剩余牙齿数量。生活质量采用日本版欧洲癌症研究与治疗组织生活质量问卷头颈部35（EORTC QLQ-H&N35）和口腔健康影响程度量表-14（OHIP-14）进行评估。计算Spearman秩相关系数，并进行多元线性回归分析以确定与生活质量独立相关的因素。结果：在单变量分析中，咀嚼功能与EORTC QLQ-H&N35的“吞咽”领域显著相关，而咬合力仅与“言语”领域相关，舌压未显示显著关联。在多元线性回归分析中，咀嚼功能与OHIP-14总分独立相关，但与EORTC QLQ-H&N35的任何领域均无显著关联。结论：咀嚼功能与上颌缺损患者在接受确定性阻塞器修复后的口腔健康相关生活质量相关。EORTC QLQ-H&N35与OHIP-14之间的关联存在差异，这两个量表评估上颌骨切除术后康复中患者报告结局的不同方面。

英文摘要

This cross-sectional study aimed to investigate the association between objectively assessed oral function and quality of life (QoL) in patients with maxillary defects after definitive obturator rehabilitation. The study participants were 67 patients who had completed prosthetic rehabilitation with a definitive obturator after maxillectomy. Masticatory performance, occlusal force, and tongue pressure were assessed as objective measures of oral function. Clinical variables included sex, age, time since surgery and prosthetic rehabilitation, defect extent, history of radiotherapy, and number of remaining teeth. QoL was evaluated using the Japanese versions of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck 35 (EORTC QLQ-H&N35) and the Oral Health Impact Profile-14 (OHIP-14). Spearman's rank correlation coefficients were calculated and multiple linear regression analysis performed to identify factors independently associated with QoL. In the univariable analyses, masticatory performance was significantly associated with the EORTC QLQ-H&N35 "Swallowing" domain, whereas occlusal force was associated only with the "Speech" domain and tongue pressure showed no significant associations. In the multiple linear regression analyses, masticatory performance was independently associated with the OHIP-14 total score but was not significantly associated with any of the EORTC QLQ-H&N35 domains. Masticatory performance was associated with oral health-related QoL in patients with maxillary defects after definitive obturator rehabilitation. The associations differed between the EORTC QLQ-H&N35 and the OHIP-14, which assess different aspects of patient-reported outcomes after maxillectomy rehabilitation.