肥胖、颅内高压与脑脊液漏之间的关系
The Relationship among Obesity, Intracranial Hypertension, and Cerebrospinal Fluid Leak.
文献信息
| PMID | 42869734 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Gabriella Ojeda-Badillo |
| 作者单位 | Beth Israel Deaconess Medical Center / Harvard Medical School, Division of Otolaryngology-Head & Neck Surgery, Shapiro Building Ground Floor, 330 Brookline Avenue, Boston, MA 02215, USA. |
| 期刊 | Otolaryngologic clinics of North America |
| SCI 分区 | Q2 |
| IF | 1.8 |
| 研究类型 | 综述 Meta · 临床 |
| 所属专科 | 耳科 |
中文摘要
特发性颅内高压（IIH）是一种以颅内压升高为特征、无可识别病变或继发病因的疾病。患者常可表现出IIH的耳鼻咽喉科表现，如搏动性耳鸣、耳闷胀感和脑脊液（CSF）漏。肥胖作为IIH和CSF漏的危险因素发挥重要作用，因为相似的病理生理过程是这两种表现的基础。理解该疾病的细微表现对于经常评估这些症状患者的耳鼻咽喉科医生很重要，并对治疗决策具有意义。在本文中，我们讨论肥胖、IIH和CSF漏之间的关系。
英文摘要
Idiopathic intracranial hypertension (IIH) is a disorder characterized by elevated intracranial pressure without identifiable lesion or secondary cause. Patients can often present with otolaryngologic manifestations of IIH, such as pulsatile tinnitus, aural fullness, and cerebrospinal fluid (CSF) leak. Obesity plays an important role as a risk factor for both IIH and CSF leak as similar pathophysiological processes underly both presentations. Understanding the nuanced presentation of this condition is important for the otolaryngologist who routinely evaluates patients with these symptoms and has implications for management decisions. In this article, we discuss the relationship among obesity, IIH, and CSF leak.