咽喉反流症状与咽喉反流性疾病：诊断与治疗
Laryngopharyngeal Symptoms and Laryngopharyngeal Reflux Disease: Diagnosis and Treatment.
文献信息
| PMID | 42869288 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Dalan Smallwood |
| 作者单位 | University of South Florida Department of Internal Medicine, Division of Allergy and Immunology, Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, 33612, USA. Electronic address: dalans3@usf.edu. |
| 期刊 | The journal of allergy and clinical immunology. In practice |
| SCI 分区 | Q1 |
| IF | 7.7 |
| 研究类型 | 综述 Meta · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
背景： 慢性咳嗽、声音嘶哑及其他咽喉症状（LPS）是常见主诉，常促使患者转诊至变态反应/免疫科医生。咽喉反流性疾病（LPRD）可引起LPS，且由于其症状与许多其他疾病重叠，理解如何临床评估和治疗该病至关重要。评估是否伴有胃食管反流病症状至关重要。通过喉镜直接观察的重要性，以及在某些情况下内镜评估和pH检测，也凸显了采取多学科方法评估疑似LPRD患者的重要性。本文综述了LPS、LPRD的病理生理学和诊断标准，以及最佳评估和管理该组患者通常所需的多学科方法。
英文摘要
Chronic cough, hoarseness, and other laryngopharyngeal symptoms (LPS) are common complaints that often prompt a referral to an allergist/immunologist. Laryngopharyngeal reflux disease (LPRD) can cause LPS, and due to its symptom overlap with many other conditions, it is critical to understand how to clinically evaluate and treat this disease. Assessing for the presence or absence of concomitant gastroesophageal reflux disease symptoms is critical. The importance of direct visualization via laryngoscopy, and in some cases endoscopic evaluation and pH testing, also highlight the importance of taking a multidisciplinary approach to evaluate suspected LPRD patients. This manuscript reviews LPS, the pathophysiology and diagnostic criteria of LPRD, and the often multidisciplinary approach required to best evaluate and manage this group of patients.