Article record

基于移动健康的口腔肌功能训练治疗阻塞性睡眠呼吸暂停的疗效与依从性

Efficacy and adherence of mobile health-based myofunctional therapy for obstructive sleep apnea.

临床研究咽喉科IF 1.7Q2

文献信息

PMID	42868897
原文	在 PubMed 查看原文 ↗
发表日期	2026
作者	Liqun Zhu 查看其他 7 位作者 Wenqian Zhong；Meihong Zhang；Chucheng Wu；Yuxiang Zhou；Jing Tao；Beiping Miao；Zhenzhang Lu
作者单位	Department of Otolaryngology Head and Neck Surgery, South China Hospital, Medical School, Shenzhen University, Shenzhen, Guangdong Province, 518116, China; Department of Otolaryngology Head and Neck Surgery, The Second People's Hospital of Shenzhen, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, China; Shenzhen Clinical Medical Research Center for Otolaryngology Diseases, The Second People's Hospital of Shenzhen, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, China. 查看其他 6 条单位信息 Department of Ophthalmology, South China Hospital, Medical School, Shenzhen University, Shenzhen, Guangdong Province, 518000, China.；Department of Otolaryngology Head and Neck Surgery, South China Hospital, Medical School, Shenzhen University, Shenzhen, Guangdong Province, 518116, China.；Department of Otorhinolaryngology, The People's Hospital of Baoan Shenzhen, Shenzhen, Guangdong Province, 518000, China.；Department of Otolaryngology Head and Neck Surgery, The Second People's Hospital of Shenzhen, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, China.；Department of Otolaryngology Head and Neck Surgery, The Second People's Hospital of Shenzhen, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, China; Shenzhen Clinical Medical Research Center for Otolaryngology Diseases, The Second People's Hospital of Shenzhen, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, China. Electronic address: miaobeiping163@163.com.；Department of Otolaryngology Head and Neck Surgery, South China Hospital, Medical School, Shenzhen University, Shenzhen, Guangdong Province, 518116, China; Department of Otolaryngology Head and Neck Surgery, The Second People's Hospital of Shenzhen, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, China; Shenzhen Clinical Medical Research Center for Otolaryngology Diseases, The Second People's Hospital of Shenzhen, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, 518035, China. Electronic address: 530639002@qq.com.
期刊	Auris, nasus, larynx
SCI 分区	Q2
IF	1.7
研究类型	临床研究 · 临床
所属专科	咽喉科

中文摘要

目的： 评估基于微信小程序的肌功能训练（MFT）对阻塞性睡眠呼吸暂停（OSA）患者疗效和依从性的影响，并与传统医院指导方案进行比较。
方法： 开展了一项平行组随机对照试验，纳入78例拒绝持续气道正压通气（CPAP）或手术治疗的OSA患者（平均年龄39.44 ± 9.82岁）。参与者被随机分配到小程序干预组（n = 39）或非干预组（n = 39）。两组均接受为期12周的口咽肌训练方案，针对软腭、舌、唇和颊肌。干预组通过定制微信应用程序接受视频指导、实时反馈和自动依从性监测，而非干预组使用纸质日记记录。随后比较两组的结果，包括多导睡眠监测结果、睡眠量表评分和依从率。
结果： 66例患者完成了研究（干预组32例，非干预组34例）。干预组的AHI改善显著优于非干预组（Δ8.92 ± 9.27 vs. Δ2.66 ± 6.80 次/小时，P < 0.001），且在所有时间点的依从率均更高（12周：73% vs. 66%，P = 0.002）。
结论： 移动健康指导的MFT显著提高了OSA患者的治疗依从性，并在核心指标AHI改善方面优于传统方式，为不能耐受CPAP的患者提供了一种数字化解决方案。

英文摘要

OBJECTIVE: To assess the impact of WeChat applet-based myofunctional therapy (MFT) on the efficacy and adherence of patients with obstructive sleep apnea (OSA) compared to conventional hospital-guided programs.
METHODS: A parallel-group randomized controlled trial was conducted, enrolling 78 patients with OSA who declined continuous positive airway pressure (CPAP) or surgical treatment (mean age 39.44 ± 9.82 years). Participants were randomly allocated to either the mini-program intervention group (n = 39) or the non-intervention group (n = 39). Both groups underwent a 12-week oropharyngeal muscle training program that targeted the soft palate, tongue, lips, and buccal muscles. The intervention group received video-based guidance, real-time feedback, and automated compliance monitoring via a customized WeChat application, whereas the non-intervention group maintained their records using paper diaries. Outcomes, including polysomnography results, sleep scale scores, and compliance rates, were subsequently compared between the two groups.
RESULTS: Sixty-six patients completed the study (32 in the intervention group and 34 in non-intervention group). Improvement in AHI was significantly better in the intervention group than in the non-intervention group (Δ8.92 ± 9.27 vs. Δ2.66 ± 6.80 beats/h, P < 0.001), and adherence rates were higher at all time points (12 weeks: 73% vs. 66%, P = 0.002).
CONCLUSIONS: Mobile health guided MFT significantly improved treatment adherence in patients with OSA and outperformed traditional modality in terms of improvement in the core metric AHI, providing a digital solution for CPAP-intolerant patients.