前庭性偏头痛及可能的前庭性偏头痛中的抑郁和焦虑症状
Depressive and Anxiety Symptoms in Vestibular Migraine and Probable Vestibular Migraine.
文献信息
| PMID | 42860634 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Chisato Fujimoto |
| 作者单位 | Department of Otolaryngology and Head and Neck Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan. |
| 期刊 | Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery |
| SCI 分区 | Q2 |
| IF | 2 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
引言： 既往有报道称，前庭性偏头痛（VM）患者更容易出现焦虑和抑郁症状。然而，VM的病理生理与焦虑和抑郁症状之间的关联仍不清楚。本研究旨在通过比较VM和可能的前庭性偏头痛（PVM）患者来探讨这种关联，基于的假设是，符合VM完整诊断标准的患者比符合PVM标准的患者更能代表该疾病的核心临床表型。
方法： 我们回顾了2018年3月开始常规测量抑郁自评量表（SDS）和状态-特质焦虑量表（STAI）至2024年12月期间，在我们诊所连续就诊的1736例患者的病历。共纳入34例VM患者和13例PVM患者。进行多元回归分析，以观察受试者的年龄、性别或VM诊断类别（VM vs. PVM）是否与SDS、STAI-1和STAI-2评分相关。
结果： VM诊断类别与SDS评分显著相关，VM患者评分高于PVM患者（p = 0.0095；事后检验效能 = 0.92）。VM诊断类别与STAI-1或STAI-2评分之间无显著关联（p = 0.542和0.367；事后检验效能 = 0.10和0.23），提示有限的统计效能可能影响了对焦虑关联的检测。
结论： VM患者比PVM患者更可能报告抑郁症状，提示VM病理生理与抑郁症状之间存在关联。
英文摘要
INTRODUCTION: It has been previously reported that patients with vestibular migraine (VM) are more prone to anxiety and depressive symptoms. However, the association between the pathophysiology of VM and anxiety and depressive symptoms is still unclear. This study aimed to investigate this association by comparing patients with VM and probable VM (PVM), based on the hypothesis that patients fulfilling the complete diagnostic criteria for VM more closely represent the core clinical phenotype of the disorder than those fulfilling the criteria for PVM.
METHODS: We reviewed the medical records of 1736 consecutive patients seen at our clinic between March 2018, when routine measurement of Self-rating Depression Scale (SDS) and State-Trait Anxiety Inventory (STAI) began, and December 2024. Thirty-four VM patients and 13 PVM patients were included. Multiple regression analyses were performed to see whether the subjects' age, sex or the VM diagnostic category (VM vs. PVM) had an association with SDS, STAI-1 and STAI-2 scores.
RESULTS: The VM diagnostic category was significantly associated with SDS scores, with VM patients showing higher scores than PVM patients (p = 0.0095; post hoc power = 0.92). There was no significant association between the VM diagnostic category and STAI-1 or STAI-2 scores (p = 0.542 and 0.367; post hoc power = 0.10 and 0.23), suggesting that limited statistical power may have affected detection of anxiety associations.
CONCLUSION: VM patients are more likely to report depressive symptoms than PVM patients, suggesting an association between VM pathophysiology and depressive symptoms.