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经TOMES治疗的孤立性喉浆细胞瘤:病例报告及文献综述。

Solitary laryngeal plasmacytoma treated by TOMES: Case report and review of the literature.

临床研究咽喉科IF 1.7Q2

文献信息

中文摘要

引言: 喉浆细胞瘤是罕见的浆细胞肿瘤,可模仿其他病变,给诊断和治疗带来挑战。其位于气道内,使得早期诊断和精准管理对于防止气道阻塞至关重要。本报告旨在描述首例记录在案的、采用经口微电极手术(TOMES)治疗的孤立性喉浆细胞瘤病例,强调其作为微创治疗选择的潜力。
病例报告: 我们描述了一名60岁男性,其喉部肿瘤最初被误诊。肿瘤位于右侧室带并延伸至同侧声带,经TOMES完全切除。组织病理学检查证实为浆细胞瘤,全身检查排除了多发性骨髓瘤。术后过程顺利,多年随访无复发。
讨论: 尽管放疗仍是孤立性髓外浆细胞瘤的标准治疗,但完全经口切除可能是一种有价值的替代方案,尤其是在气道通畅受到威胁时。TOMES提供精确切割和出色的止血控制,能够以最小的并发症完全切除肿瘤并保留喉功能。
结论: 这是首例成功采用TOMES治疗的孤立性喉浆细胞瘤病例报告。这种微创技术是喉部肿瘤手术治疗中有前景的工具。

英文摘要

INTRODUCTION: Laryngeal plasmacytomas are rare plasma cell neoplasms that can mimic other lesions, posing a diagnostic and therapeutic challenge. Their location within the airway makes early diagnosis and precise management crucial to prevent airway compromise. This report aims to describe the first documented case of solitary laryngeal plasmacytoma managed with transoral microelectrode surgery (TOMES), highlighting its potential as a minimally invasive therapeutic option.
CASE REPORT: We describe a 60-year-old man with a laryngeal tumour initially misinterpreted. The tumor, located in the right ventricular band and extending to the ipsilateral vocal fold, was completely resected with TOMES. Histopathological examination confirmed the diagnosis of plasmacytoma, and systemic investigations ruled out multiple myeloma. The postoperative course was uneventful, with no recurrence after years of follow-up.
DISCUSSION: Although radiotherapy remains the standard treatment for solitary extramedullary plasmacytoma, complete transoral resection may be a valuable alternative, particularly when airway patency is threatened. TOMES provides precise cutting and excellent haemostatic control, enabling complete tumour excision with minimal morbidity and preservation of laryngeal function.
CONCLUSION: This is the first reported case of solitary laryngeal plasmacytoma successfully treated with TOMES. This minimally invasive technique represents a promising tool in the surgical management of laryngeal tumours.