Article record

基于生理外周听觉前端模块的圆窗刺激双耳响度模型

A binaural loudness model for evaluating round-window stimulation based on a physiological peripheral auditory front-end module.

基础研究耳科IF 3.2Q1

文献信息

PMID	42849139
原文	在 PubMed 查看原文 ↗
发表日期	2026
作者	Zhaohai Liu 查看其他 5 位作者 Houguang Liu；Xinjian He；Thomas Lenarz；Hannes Maier；Brian C J Moore
作者单位	School of Mechanical and Electrical Engineering, China University of Mining and Technology, Xuzhou, 221116, China; School of Traffic engineering, Nanjing Institute of Technology, Nanjing, 211167, China. 查看其他 4 条单位信息 School of Mechanical and Electrical Engineering, China University of Mining and Technology, Xuzhou, 221116, China; Research Institute of Occupational Health, China University of Mining and Technology, Xuzhou, 221116, China; Department of Otolaryngology/NIFE, Hannover Medical School, Hannover, 30625, Germany; Cluster of Excellence "Hearing4all.connects", Hannover Medical School, Hannover, 30625, Germany. Electronic address: liuhg@cumt.edu.cn.；Research Institute of Occupational Health, China University of Mining and Technology, Xuzhou, 221116, China.；Department of Otolaryngology/NIFE, Hannover Medical School, Hannover, 30625, Germany; Cluster of Excellence "Hearing4all.connects", Hannover Medical School, Hannover, 30625, Germany.；Cambridge Hearing Group, Department of Psychology, University of Cambridge, Cambridge, CB2 3EB, United Kingdom.
期刊	Hearing research
SCI 分区	Q1
IF	3.2
研究类型	基础研究 · 基础／转化
所属专科	耳科

中文摘要

背景： 一些主动中耳植入物使用圆窗刺激将其应用扩展到混合性听力损失。然而，当前的响度模型无法预测圆窗刺激下的响度，这阻碍了验配程序的发展。方法：本文提出了一种新的圆窗刺激响度模型。该模型由一个外周听觉前端模块（将麦克风拾取的信号转换为圆窗刺激和有效耳蜗响应）和一个响度感知后端模块（将耳蜗响应转换为响度）组成。通过将预测结果与多种刺激的耳蜗响应实验数据进行比较，验证了前端模块的准确性。通过将预测结果与纯音和噪声响度的实验数据进行比较，验证了后端模块的准确性。结果：在圆窗刺激下，响度随驱动电压幅度的增加与声刺激一致，但等响曲线的形状与声刺激不同，反映了不同的传递函数和换能器特性。当应用频率相关校正以考虑这一点时，预测的等响曲线与声刺激相似。此外，模型对双耳同侧和双耳异侧噪声的预测结果与声刺激略有偏差，而纯音的模型预测结果与声刺激更一致。结论：这项研究为圆窗刺激主动中耳植入物验配程序的开发奠定了基础。

英文摘要

Some active middle-ear implants use round-window stimulation to extend their application to mixed hearing loss. However, current loudness models are unable to predict loudness under round-window stimulation, which prevents the development of fitting procedures. This paper presents a new loudness model for round-window stimulation. The model consists of a peripheral auditory front-end module, which translates the signal picked up by the microphone to round-window stimulation and to effective cochlear response, and a loudness perception back-end module for converting the cochlear response into loudness. The accuracy of the front-end module was validated by comparing the predicted results with experimental data on cochlear responses to a variety of stimuli. The accuracy of the back-end module was validated by comparing the predicted results with experimental data on the loudness of pure tones and noise. The increase in loudness with increasing drive voltage amplitude under round-window stimulation was consistent with that for acoustic stimulation, but the shapes of the equal-loudness contours were different from those for acoustic stimulation, reflecting the different transfer functions and the characteristics of the transducer. When a frequency-dependent correction was applied to allow for this, the predicted equal-loudness contours were similar to those for acoustic stimulation. Additionally, the model-predicted results for diotic and dichotic noise exhibited slight deviations from those for acoustic stimulation, whereas the model-predicted results for pure tones aligned more consistently with those for acoustic stimulation. This research forms the foundation for the development of fitting procedures for round-window stimulating active middle ear implants.