髓鞘少突胶质细胞糖蛋白抗体相关疾病中的耳蜗植入。

文献信息

中文摘要

髓鞘少突胶质细胞糖蛋白抗体相关疾病（MOGAD）是一种神经免疫性脱髓鞘疾病，可表现为中枢性或外周性感音神经性听力损失（SNHL）。本病例描述了一名43岁女性，患有MOGAD和重度右侧SNHL，经神经免疫治疗后未见改善。进一步的免疫学和影像学检查未见异常。该患者接受了右侧耳蜗植入（CI），无并发症，且言语识别能力显著改善。尽管可能存在中枢性SNHL，部分MOGAD患者仍可能从CI中获益，因此MOGAD不应被视为耳蜗植入的绝对禁忌证。

英文摘要

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a neuroimmunologic demyelinating disorder that may present with central or peripheral sensorineural hearing loss (SNHL). This case describes a 43-year-old female with MOGAD and profound right-sided SNHL who did not improve with neuroimmunologic therapy. Additional immunologic and radiographic workup was unrevealing. The patient underwent right cochlear implantation (CI) without complication and with significant improvement in her speech recognition. Despite the possibility of central SNHL, select patients with MOGAD may benefit from CI, and thus MOGAD should not be considered an absolute contraindication to cochlear implantation.