伴与不伴阻塞性睡眠呼吸暂停的骨性III类受试者的特征。
Characteristics of skeletal Class III subjects with and without obstructive sleep apnea.
文献信息
| PMID | 42843761 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Jakkapat Karusan |
| 作者单位 | Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. |
| 期刊 | Journal of stomatology, oral and maxillofacial surgery |
| SCI 分区 | Q2 |
| IF | 2.4 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 鼻科 |
中文摘要
目的： 本研究旨在探讨伴与不伴阻塞性睡眠呼吸暂停（OSA）的骨性III类受试者的临床、骨骼、咽气道及睡眠特征。
方法： 对46名受试者（18名伴OSA，28名不伴OSA）进行回顾性病例对照研究。评估了病历、头影测量分析、锥形束计算机断层扫描、泰文版Epworth嗜睡量表、改良STOP-Bang问卷（SBQ）以及睡眠研究结果。
结果： OSA组以男性为主，并表现出更高的体重指数（BMI）和更大的颈围。睡眠分析显示，与不伴OSA的受试者相比，伴OSA的受试者具有更高的改良SBQ评分、更高的打鼾程度、增加的浅睡眠以及减少的REM睡眠阶段。在骨骼变量中，仅下颌长度（Go-Gn）在OSA组中显著较短。咽气道显示悬雍垂更长、气道长度增加以及咽气道上段横向尺寸更窄。单变量分析确定男性、BMI >25 kg/m²、颈围 >40 cm、改良SBQ评分 ≥3、打鼾以及下颌长度 <80 mm为与OSA相关的因素。在多变量logistic回归分析中，男性（调整OR = 8.11，95%CI：1.10-59.51，p = 0.040）和下颌长度 <80 mm（调整OR = 8.40，95%CI：1.05-67.17，p = 0.045）仍与OSA显著相关。
结论： 在骨性III类受试者中，OSA与男性和较短的下颌长度相关，而未调整分析中观察到区域气道形态的差异。整合临床和影像学参数可能为识别OSA风险增加的骨性III类患者提供补充信息。
英文摘要
OBJECTIVE: This study aimed to investigate the clinical, skeletal, pharyngeal airway, and sleep characteristics of skeletal Class III subjects with and without obstructive sleep apnea (OSA).
METHOD: A retrospective case-control study was conducted in 46 subjects (18 with OSA and 28 without OSA). Medical records, cephalometric analyses, cone-beam computed tomography, Thai versions of the Epworth Sleepiness Scale, modified STOP-Bang Questionnaire (SBQ), and sleep study results were evaluated.
RESULTS: The OSA group predominantly comprised males and exhibited higher body mass index (BMI) and larger neck circumference. Sleep analysis showed that subjects with OSA had higher modified SBQ scores, higher snoring level, increased light sleep, and reduced REM sleep stages compared with non-OSA subjects. Among skeletal variables, only mandibular length (Go-Gn) was significantly shorter in the OSA group. Pharyngeal airway revealed a longer uvula, increased airway length, and narrower lateral dimensions of the upper segment of pharyngeal airway. Univariable analysis identified male sex, BMI >25 kg/m², neck circumference >40 cm, modified SBQ score ≥3, snoring, and mandibular length <80 mm as factors associated with OSA. In multivariable logistic regression analysis, male sex (adjusted OR = 8.11, 95%CI: 1.10-59.51, p = 0.040) and mandibular length <80 mm (adjusted OR = 8.40, 95%CI: 1.05-67.17, p = 0.045) remained significantly associated with OSA.
CONCLUSIONS: Within skeletal Class III subjects, OSA was associated with male sex and shorter mandibular length, while differences in regional airway morphology were observed in the unadjusted analyses. Integrating clinical and imaging parameters may provide complementary information for identifying skeletal Class III patients at increased risk of OSA.