纤维肌痛患者睡眠与嗓音障碍之间的相关性
Correlation Between Sleep and Voice Disorders in Patients with Fibromyalgia.
文献信息
| PMID | 42838784 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Abdul-Latif Hamdan |
| 作者单位 | Department of Otolaryngology-Head and Neck Surgery, American University of Beirut Medical Center, Beirut, Lebanon. |
| 期刊 | Journal of voice : official journal of the Voice Foundation |
| SCI 分区 | Q1 |
| IF | 2.4 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
目的： 探讨纤维肌痛综合征（FMS）患者睡眠与嗓音障碍之间的联系。
研究设计： 横断面研究 方法：于2026年4月至2026年6月期间，从一家三级转诊中心的风湿病门诊招募年龄在18至65岁、诊断为FMS的成年患者。纤维肌痛综合征由经委员会认证的风湿病学家根据2016年美国风湿病学会诊断标准进行诊断。次要结局指标包括嗓音障碍指数-10（VHI-10）和声音嘶哑视觉模拟量表（VAS）。
结果： 共纳入101例患者，其中63例为FMS患者，38例为对照。所有纳入患者均为女性。FMS组与对照组之间的平均VHI-10和VAS评分差异具有统计学意义（分别为6.10 ± 7.20 vs 1.65 ± 1.30，P < 0.001；2.00 ± 1.69 vs 1.18 ± 0.393，P = 0.004）。FMS组与对照组之间的平均PSQI评分差异具有统计学意义（8.65 ± 4.02 vs 5.97 ± 4.10，P = 0.007），即使在调整混杂人口学变量后也是如此（调整后P = 0.033）。VHI-10与PSQI评分之间也存在轻度正相关（调整后系数 = 0.340，调整后P = 0.080）。然而，在调整混杂变量后，该相关性不再显著（P = 0.080，调整后系数 = 0.340）。
结论： 与对照组相比，FMS患者中睡眠和嗓音障碍更为常见。睡眠障碍与自评嗓音障碍之间存在关联，尽管程度较轻，这强调需要对出现发声困难的FMS患者进行睡眠障碍筛查。
英文摘要
OBJECTIVES: To investigate the link between sleep and voice disorders in patients with fibromyalgia syndrome (FMS).
STUDY DESIGN: Cross-sectional METHOD: Adult patients aged 18 to 65 years with a diagnosis of FMS were recruited from the Rheumatology Clinic of a tertiary referral center between April 2026 and June 2026. Fibromyalgia syndrome was diagnosed by a board-certified rheumatologist based on the 2016 American College of Rheumatology diagnostic criteria. Secondary outcome measures included the Voice Handicap Index-10 (VHI-10) and the Visual Analog Scale (VAS) for hoarseness.
RESULTS: A total of 101 patients, 63 patients with FMS and 38 controls, were included in the study. All patients included were females. There was a statistically significant difference in the mean VHI-10 and VAS scores between the FMS group and the control group (6.10 ± 7.20 vs 1.65 ± 1.30, P < 0.001, and 2.00 ± 1.69 vs 1.18 ± 0.393, P = 0.004, respectively). There was a statistically significant difference in the mean PSQI score between the FMS group and controls (8.65 ± 4.02 vs 5.97 ± 4.10, P = 0.007), even after adjusting for confounding demographic variables (adjusted P = 0.033). There was also a mild positive association between VHI-10 and PSQI scores (adjusted coefficient = 0.340, adjusted P = 0.080). However, the correlation was no longer significant after adjusting for confounding variables (P = 0.080, adjusted coefficient = 0.340).
CONCLUSION: Sleep and voice disorders are more common in patients with FMS in comparison to controls. The presence of an association, albeit mild, between sleep disturbance and self-perceived voice handicap underscores the need to screen for sleep disorders in FMS patients presenting with dysphonia.