Article record

被纳入瑞典国家气道登记册的儿童具有更高的家族性特应性、更严重的疾病和更高的社会经济地位。

Children Captured in the Swedish National Airway Register Have Increased Familial Atopy, More Severe Disease and Higher Socioeconomic Status.

临床研究鼻科IF 2.4Q2

文献信息

PMID	42837199
原文	在 PubMed 查看原文 ↗
发表日期	2026
作者	Hanna Karim 查看其他 7 位作者 Cecilia Lundholm；Bronwyn Brew；Emma Caffrey Osvald；Caroline Stridsman；Resthie R Putri；Jon Roald Konradsen；Catarina Almqvist
作者单位	Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden. 查看其他 6 条单位信息 Astrid Lindgren's Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.；Centre for Big Data Research in Health, University of New South Wales, Kensington, Australia.；School of Medicine and Public Health, University of Newcastle, Newcastle, Australia.；Pediatric Allergy and Pulmonology Unit, Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.；Department of Public Health and Clinical Medicine, the OLIN and Sunderby Research Unit, Umeå University, Umeå, Sweden.；Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
期刊	Acta paediatrica (Oslo, Norway : 1992)
SCI 分区	Q2
IF	2.4
研究类型	临床研究 · 临床
所属专科	鼻科

中文摘要

目的： 我们估计了瑞典国家气道登记册（SNAR）中记录儿童的覆盖率，并识别了哮喘及中重度哮喘患儿中登记的预测因素。
方法： 本研究纳入85 656名5-17岁哮喘儿童，出生于2000-2019年，居住在斯德哥尔摩。这些儿童通过国家和区域健康登记册中的诊断和配发药物被识别。评估了SNAR中的登记情况。采用逻辑回归比较已登记和未登记儿童的特征，关联以比值比（OR）和95%置信区间（CI）表示。
结果： 总体而言，33 815名（39.5%）哮喘儿童在SNAR中登记。登记在患有过敏性鼻炎的儿童中更为常见（OR 1.83，95% CI 1.77-1.88），父母有哮喘和过敏性鼻炎（母亲OR 1.47，95% CI 1.43-1.51），父母收入和受教育程度较高（OR 1.09，95% CI 1.05-1.12），以及中重度哮喘（OR 1.37，95% CI 1.32-1.42）。在中重度哮喘亚队列中结果相似。
结论： 斯德哥尔摩近40%的哮喘儿童在SNAR中登记，他们更可能具有家族性特应性、较高的社会经济地位和更严重的疾病。SNAR正在发展以提高覆盖率、支持标准化登记并改善照护。

英文摘要

AIM: We estimated the coverage of children recorded in the Swedish National Airway Register (SNAR) and identified predictors of registration among those with asthma and moderate to severe asthma.
METHODS: This study comprised 85 656 children aged 5-17 years with asthma, born 2000-2019 and living in Stockholm. The children were identified through diagnoses and dispensed medication in national and regional health registers. Registration in the SNAR was assessed. Logistic regression compared characteristics of registered and unregistered children, with associations presented as odds ratios (OR) and 95% confidence intervals (CI).
RESULTS: Overall, 33 815 (39.5%) of children with asthma were registered in the SNAR. Registration was more common among children with allergic rhinitis (OR 1.83, 95% CI 1.77-1.88), parental asthma and allergic rhinitis (maternal OR 1.47, 95% CI 1.43-1.51), higher parental income and education (OR 1.09, 95% CI 1.05-1.12), and moderate to severe asthma (OR 1.37, 95% CI 1.32-1.42). Findings were similar in the moderate to severe asthma sub-cohort.
CONCLUSION: Nearly 40% of children with asthma in Stockholm were registered in the SNAR, and they were more likely to have familial atopy, higher socioeconomic status, and more severe disease. The SNAR is being developed to increase coverage, support standardized registration, and improve care.