Article record

宏基因组下一代测序在识别继发于鼻窦炎的儿童脑脓肿厌氧病原体中的效用：一例病例报告。

Utility of Metagenomic Next-Generation Sequencing in Identifying Anaerobic Pathogens in a Pediatric Brain Abscess Secondary to Sinusitis: A Case Report.

临床研究鼻科IF 0.6Q3

文献信息

PMID	42835638
原文	在 PubMed 查看原文 ↗
发表日期	2026
作者	Risa Nagase 查看其他 9 位作者 Kunihiro Oba；Mari Asakura；Masashi Ogasawara；Masahiro Noda；Yusuke Yamada；Asayo Furukawa；Naoki Kojima；Masanori Hashino；Kazuhiro Horiba
作者单位	Department of Pediatrics Showa General Hospital Kodaira Japan. 查看其他 4 条单位信息 Department of Neurosurgery Showa General Hospital Kodaira Japan.；Department of Otolaryngology Showa General Hospital Kodaira Japan.；Department of Critical Care and Emergency Medicine Showa General Hospital Kodaira Japan.；Laboratory of Microbial Genomics, Pathogen Genomics Center National Institute of Infectious Diseases, Japan Institute for Health Security Shinjuku-ku Japan.
期刊	Clinical case reports
SCI 分区	Q3
IF	0.6
研究类型	临床研究 · 临床
所属专科	鼻科

中文摘要

在本例儿童脑脓肿病例中，宏基因组下一代测序（mNGS）鉴定出一种传统培养方法未能检出的厌氧细菌，从而为抗菌药物管理提供了具有临床相关性的信息。这表明mNGS可能是优化治疗策略的有用辅助手段。

英文摘要

In this pediatric brain abscess case, metagenomic next-generation sequencing (mNGS) identified an anaerobic bacterium that remained undetected using conventional culture methods, thus providing clinically relevant information for antimicrobial management. This indicates that mNGS may be a useful adjunct for optimizing treatment strategies.