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儿童人工耳蜗植入后的不使用率:系统综述与荟萃分析。

Non-usage rates after paediatric cochlear implantation: A systematic review and meta-analysis.

综述 Meta耳科IF 1.7Q2

文献信息

中文摘要

目的: 确定儿童人工耳蜗(CI)接受者中长期不使用和部分使用的患病率,并识别与依从性欠佳相关的因素。
数据来源: 对包括PubMed、Embase和Cochrane Library在内的主要电子数据库进行了系统检索,以识别报告儿童人群CI使用模式的研究。
综述方法: 我们按照PRISMA指南对29项研究(n = 2595)进行了系统综述和荟萃分析。使用随机效应模型和广义线性混合模型计算合并患病率估计值。
结果: 不使用的合并患病率为4.45%(95% CI:2.21-8.78,p < 0.0001),部分使用(<8小时/天)为8.99%(95% CI:5.91-13.44,p < 0.0001)。不使用率在大洋洲最高,为27.27%(95% CI = 9.05-58.57),在欧洲最低,为1.99%(95% CI:1.00-3.94)。与正常人群相比,特定临床亚组中的不使用率也显著更高(16.29% vs 2.29%)。听力损失持续时间较长与部分使用患病率较高相关(系数0.477,p < 0.001)。与12-24个月相比,早期植入(≤12个月)与部分使用减少相关(6.89% vs 16.81%)。未发现与随访持续时间、性别或植入侧别存在显著关联。
结论: 超过十分之一的接受者表现出长期依从性欠佳,并因地区、临床亚组、听力损失持续时间和植入年龄而异。需要有针对性的、风险分层的策略来改善依从性和长期结局。

英文摘要

OBJECTIVE: To determine the prevalence of long-term cochlear implant (CI) non-use and partial use in paediatric recipients and identify factors associated with suboptimal adherence.
DATA SOURCES: A systematic search of major electronic databases including PubMed, Embase, and the Cochrane Library was performed to identify studies reporting CI usage patterns in paediatric populations.
REVIEW METHODS: We conducted a systematic review and meta-analysis of 29 studies (n = 2595) following PRISMA guidelines. Pooled prevalence estimates were calculated using random-effects models with generalized linear mixed model.
RESULTS: The pooled prevalence of non-use was 4.45% (95% CI: 2.21-8.78, p < 0.0001) and partial use (<8 h/day) was 8.99% (95% CI: 5.91-13.44, p < 0.0001). Non-use was highest in Oceania at 27.27% (95% CI = 9.05-58.57), and lowest in Europe at 1.99% (95% CI: 1.00-3.94). Compared to normal population, non-use rates are also significantly higher among specific clinical subgroups (16.29% vs 2.29%). Longer duration of hearing loss was associated with a higher prevalence of partial-use (coefficient 0.477, p < 0.001). Compared to 12-24 months, early implantation (=<12 months) was associated with reduced partial use (6.89% vs 16.81%). No significant associations were found with follow up duration, sex or implant laterality.
CONCLUSION: More than one-tenth of recipients demonstrated suboptimal long-term adherence, varying by region, clinical subgroups, hearing loss duration, and implantation age. Targeted, risk-stratified strategies are needed to improve adherence and long-term outcomes.