慢性中耳炎患者生活质量的决定因素：一项多变量分析
Determinants of quality of life among patients with chronic otitis media: a multivariable analysis.
文献信息
| PMID | 42827162 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Hakan Kara |
| 作者单位 | Istanbul Faculty of Medicine, Department of Otorhinolaryngology & Head and Neck Surgery, Istanbul University, Istanbul, Turkey. |
| 期刊 | European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery |
| SCI 分区 | Q1 |
| IF | 2.3 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
目的： 我们的研究旨在使用慢性中耳炎问卷-12（COMQ-12）作为疾病特异性评估工具，确定与慢性中耳炎（COM）患者生活质量（QoL）相关的独立人口学和临床因素。应用多变量回归分析以确定哪些变量对患者报告的生活质量影响最显著。
方法： 于2022年5月至2023年5月在一家三级转诊中心对299名成年参与者进行了一项横断面观察性研究。所有参与者完成了两份问卷：第一份收集社会人口学和临床数据，第二份是经过验证的COMQ-12。进行了耳镜检查和听力学检查。计算了双耳听力障碍（BHI）。使用多变量线性回归分析来确定与较高COMQ-12评分独立相关的因素。
结果： COMQ-12平均评分为28.17±12.03。多变量回归分析显示，较年轻年龄（p=0.017）、存在耳漏（p<0.001）、耳鸣（p=0.007）和较高的BHI（p=0.025）与较高的COMQ-12评分密切相关。生活质量与性别、教育水平、疾病类型或侧别、吸烟状况和合并症负担等变量之间没有统计学显著关系。
结论： 较年轻年龄、耳漏、耳鸣和BHI与较高的COMQ-12评分独立相关，表明COM患者的生活质量降低。在COM的管理和治疗中考虑这些因素可能会改善患者的生活质量。
英文摘要
PURPOSE: Our study aimed to identify the independent demographic and clinical factors associated with quality of life (QoL) in patients with chronic otitis media (COM), using the Chronic Otitis Media Questionnaire-12 (COMQ-12) as a disease-specific assessment tool. Multivariable regression analysis was applied to determine which variables most significantly influence patient-reported QoL.
METHODS: A cross-sectional, observational study was conducted on 299 adult participants at a tertiary referral center between May 2022 and May 2023. All participants completed two questionnaires: the first collected sociodemographic and clinical data, and the second was the validated COMQ-12. Otoscopic and audiological examinations were performed. Binaural hearing impairment (BHI) was calculated. Multivariable linear regression analysis was used to identify factors independently associated with higher COMQ-12 scores.
RESULTS: The mean COMQ-12 score was 28,17 ± 12,03. Multivariable regression analysis revealed that younger age (p = 0.017), presence of ear discharge (p < 0.001), tinnitus (p = 0.007) and higher BHI (p = 0.025) were strongly associated with higher COMQ-12 scores. There was no statistically significant relationship between QoL and variables such as gender, educational level, disease type or laterality, smoking status and comorbidity burden.
CONCLUSIONS: Younger age, ear discharge, tinnitus and BHI were independently associated with higher COMQ-12 scores indicating reduced QoL in patients with COM. Consideration of these factors in the management and treatment of COM may improve patient's QoL.