过敏性鼻炎中精神症状、解离体验与童年创伤的调查研究，以及这些因素之间临床关系的评估。
Investigation of psychiatric symptoms, dissociative experiences, and childhood trauma in allergic rhinitis, and evaluation of the clinical relationship between these factors.
文献信息
| PMID | 42824918 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Mustafa Altintas |
| 作者单位 | Department of Otorhinolaryngology, Antalya Training and Research Hospital, University of Health Sciences, Antalya, Türkiye. |
| 期刊 | Frontiers in psychiatry |
| SCI 分区 | Q2 |
| IF | 4.4 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 鼻科 |
中文摘要
背景： 在本研究中，我们旨在评估过敏性鼻炎（AR）患者的抑郁和焦虑症状、童年创伤及解离体验水平，并将其与健康对照进行比较。此外，探讨AR患者中童年创伤、抑郁症状与解离体验之间的关联。
方法： 研究样本由152名成人（76名AR患者和76名健康对照）组成，他们就诊于耳鼻咽喉科门诊。数据通过个人信息表以及标准化的自评量表收集，包括童年创伤（童年创伤问卷 - CTQ-28）、焦虑和抑郁（医院焦虑抑郁量表 - HADS）以及解离体验（解离体验量表 - DES）。
结果： 患者组与对照组在所有参数上均存在显著差异（p<0.05）。患者组表现出显著更高水平的童年创伤、焦虑和抑郁症状以及解离体验。相关分析显示，在AR患者中，童年创伤与抑郁症状和解离体验均显著相关。此外，回归分析表明，童年创伤对AR患者抑郁的严重程度有显著贡献，而解离症状的存在进一步增加了抑郁的风险。
结论： 本研究提供了过敏性鼻炎中童年创伤、抑郁和解离体验之间存在正相关关系的证据，强调它们作为该疾病潜在风险因素的可能作用。因此，精神科评估对于AR患者的治疗成功至关重要且必要。
英文摘要
BACKGROUND: In this study, we aimed to evaluate levels of depression and anxiety symptoms, childhood trauma, and dissociative experiences in patients with allergic rhinitis (AR) and compare them with healthy controls. Additionally, investigate the association between childhood trauma, depressive symptoms, and dissociative experiences in AR patients.
METHODS: The study sample consisted of 152 adults (76 AR patients and 76 healthy controls) who presented to the otorhinolaryngology outpatient clinic. Data were collected using a personal information form and standardized self-report scales for childhood trauma (Childhood Trauma Questionnaire - CTQ-28), anxiety and depression (Hospital Anxiety and Depression Scale - HADS), and dissociative experiences (Dissociative Experiences Scale - DES).
RESULTS: Significant differences were found between the patient and control groups in terms of all parameters (p<0.05). The patient group showed significantly higher levels of childhood trauma, anxiety and depressive symptoms, and dissociative experiences. Correlation analyses revealed a significant correlation between childhood trauma and both depressive symptoms and dissociative experiences in AR patients. Furthermore, regression analysis showed that childhood trauma significantly contributed to the severity of depression in AR patients, while the presence of dissociative symptoms further increased the risk of depression.
CONCLUSIONS: This study presents evidence of a positive association between childhood trauma, depression, and dissociative experiences in allergic rhinitis, highlighting their potential roles as risk factors for the condition. Therefore, psychiatric evaluation is crucial and necessary for treatment success in AR patients.