舌根巨大骨性迷芽瘤：病例报告及文献复习。
Large Osseous Choristoma of the Tongue Base: A Case Report and Literature Review.
文献信息
| PMID | 42822721 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Yangyang Xia |
| 作者单位 | Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, National Center for Stomatology, National Clinical Research Center for Oral Diseases, National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing 100081, China. |
| 期刊 | Journal of stomatology, oral and maxillofacial surgery |
| SCI 分区 | Q2 |
| IF | 2.4 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
背景： 骨性迷芽瘤是一种罕见的良性病变，由异位软组织部位中的成熟骨组织构成，最常见于舌后部。我们报告一名9岁女孩，有1年舌根病变缓慢增大病史，导致吞咽困难和睡眠时打鼾。方法：增强计算机断层扫描显示一个边界清晰、均匀骨密度的病变，大小为4.0 × 3.8 × 4.1 cm，无强化或邻近软组织侵犯。结果：通过舌背入路将病变完全切除。组织病理学检查显示成熟骨组织，伴有骨小梁和骨髓腔，证实为骨性迷芽瘤。恢复顺利，3个月时无临床复发。结论：尽管舌根巨大骨性迷芽瘤为良性，仍可能引起功能性症状。计算机断层扫描提供了有用的诊断线索，而明确诊断依赖于组织病理学。完整手术切除仍是首选治疗方法。
英文摘要
Osseous choristoma is a rare benign lesion composed of mature bone in an ectopic soft-tissue site, most often the posterior tongue. We report a 9-year-old girl with a 1-year history of a slowly enlarging tongue-base lesion causing dysphagia and snoring during sleep. Contrast-enhanced computed tomography showed a well-circumscribed, homogeneous bony-density lesion measuring 4.0 × 3.8 × 4.1 cm without enhancement or adjacent soft-tissue invasion. The lesion was completely excised through a dorsal tongue approach. Histopathological examination demonstrated mature osseous tissue with bony trabeculae and marrow cavities, confirming osseous choristoma. Recovery was uneventful, with no clinical recurrence at 3 months. Large tongue-base osseous choristomas may cause functional symptoms despite their benign nature. Computed tomography provides a useful diagnostic clue, while definitive diagnosis depends on histopathology. Complete surgical excision remains the treatment of choice.