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食管结核模拟肿瘤:一例HIV感染患者的病例报告

Esophageal tuberculosis mimicking a neoplasm in a patient with HIV infection.

临床研究咽喉科IF 2.5Q1

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中文摘要

结核病(TB)仍然是全球范围内发病和死亡的主要原因,尤其是在人类免疫缺陷病毒(HIV)感染患者中。食管受累是肺外结核极为罕见的表现。由于其临床和内镜特征,它可能模拟肿瘤性疾病,从而使早期诊断复杂化。我们报告了一例免疫功能低下患者,表现为全身症状和吞咽困难。上消化道内镜检查显示一个大的溃疡性食管病变,高度提示恶性肿瘤;然而,组织病理学和微生物学检查证实了其感染性病因。

英文摘要

Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide, particularly among patients with human immunodeficiency virus (HIV) infection. Esophageal involvement is an exceedingly rare manifestation of extrapulmonary tuberculosis. Owing to its clinical and endoscopic features, it may mimic neoplastic disease, thereby complicating early diagnosis. We present the case of an immunocompromised patient with constitutional symptoms and dysphagia. Upper gastrointestinal endoscopy revealed a large ulcerated esophageal lesion highly suggestive of malignancy; however, histopathological and microbiological examination confirmed its infectious etiology.