草莓样牙龈炎作为老年女性肉芽肿性多血管炎诊断线索：一例病例报告
Strawberry Gingivitis as a Diagnostic Clue to Granulomatosis With Polyangiitis in an Older Woman: A Case Report.
文献信息
| PMID | 42808490 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Qiyu Chen |
| 作者单位 | Nanjing Stomatological Hospital, Affiliated Hospital of Medical School, Research Institute of Stomatology, Nanjing University, Nanjing, China. |
| 期刊 | Gerodontology |
| SCI 分区 | Q3 |
| IF | 2.5 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 鼻科 |
中文摘要
背景： 草莓样牙龈炎是肉芽肿性多血管炎（GPA）的一种特征性但未被充分认识的口腔表现，其可能导致长期感觉损伤，常被忽视。
病例介绍： 一名60岁女性，患有草莓样牙龈炎、咳嗽和听力损失，符合2022年ACR/EULAR的GPA分类标准（评分13分），通过综合临床、血清学、影像学和组织病理学评估确立诊断。诱导治疗使口腔病变消退，但18个月随访显示双侧耳聋和失明。
结论： 草莓样牙龈炎是GPA的高度特征性但非特异性的体征。即使短期控制良好，患者仍面临进行性感觉损伤的风险，强调需要长期随访。
英文摘要
BACKGROUND: Strawberry gingivitis is a characteristic but under-recognised oral manifestation of granulomatosis with polyangiitis (GPA), with potential for long-term sensory damage often overlooked.
CASE PRESENTATION: A 60-year-old woman with strawberry gingivitis, cough, and hearing loss fulfilled the 2022 ACR/EULAR classification criteria for GPA (score 13), with the diagnosis established through integrated clinical, serological, radiological, and histopathological assessment. Induction therapy resolved the oral lesions, but 18-month follow-up showed bilateral deafness and blindness.
CONCLUSIONS: Strawberry gingivitis is a highly characteristic, though not pathognomonic, sign of GPA. Even with good short-term control, patients risk progressive sensory damage, emphasising the need for long-term follow-up.