竹节样结节：44例患者的回顾性研究。

文献信息

中文摘要

目的： 竹节样结节（BNs）是声带罕见的炎性病变，常与自身免疫性疾病相关。本研究旨在通过病例系列识别其流行病学特征和治疗方法。
材料和方法： 对1986年至2020年间疑似BNs的患者进行回顾性多中心病历审查。
结果： 44例患者符合纳入标准。均为女性。诊断时平均年龄为44岁（±11）。BNs多为双侧，但5%的患者表现为单侧形式。64%的患者（28/44）已知患有自身免疫性疾病（AID），而18%（5/28）的患者是在发现BNs后继发诊断AID。所有患者均接受了言语治疗。45%（20/44）的患者接受了最受累声带病变的手术切除。其中10%（2/20）需要对侧声带二次手术。首次就诊后平均随访时间为15个月。67%的患者报告治疗后改善。接受手术的患者中，55%（11/20）发声困难改善，15%（3/20）保持稳定；其余失访（6/20）。仅接受言语治疗的患者中，31%（5/16）发声困难改善，6%（1/16）保持稳定，6%（1/16）恶化；56%（9/16）失访。
结论： 本系列证实了文献中的主要数据。它强调了筛查潜在自身免疫性疾病的意义。

英文摘要

OBJECTIVE: Bamboo nodes (BNs) are rare inflammatory lesions of the vocal folds, often associated with autoimmune disease. The aim of this study was to identify epidemiological characteristics and treatments in a case series.
MATERIAL AND METHODS: Retrospective multicenter chart review of patients with suspected BNs between 1986 and 2020.
RESULTS: Forty-four patients met the inclusion criteria. All were female. Mean age at diagnosis was 44 years (±11). BNs were mostly bilateral but 5% of patients presented unilateral forms. Sixty-four percent of patients (28/44) were known to have autoimmune disease (AID), while AID was diagnosed secondary to the discovery of BNs in 18% (5/28). All patients received speech therapy. Forty-five percent (20/44) underwent surgical resection of the lesion on the most affected vocal fold. Ten percent of these (2/20) required secondary surgery on the contralateral fold. Mean follow-up after first consultation was 15 months. Sixty-seven percent of patients reported improvement after treatment. Dysphonia improved in 55% of patients who were operated on (11/20), and remained stable in 15% (3/20); the others were lost to follow-up (6/20). Dysphonia improved in 31% of patients who received exclusive speech therapy (5/16), remained stable in 6% (1/16), and worsened for 6% (1/16); 56% of these patients (9/16) were lost to follow-up.
CONCLUSIONS: This series confirms the main data in the literature. It highlights the interest of screening for an underlying autoimmune condition.