序贯四通道神经肌肉电刺激对老年肌少症性吞咽障碍患者舌骨运动、吞咽安全性和经口摄食的影响：一项随机对照试验
Effects of Sequential 4-Channel Neuromuscular Electrical Stimulation on Hyoid Excursion, Swallowing Safety and Oral Intake in Older Adults With Sarcopenic Dysphagia: A Randomized Controlled Trial.
文献信息
| PMID | 42805782 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Ji-Su Park |
| 作者单位 | Research Institute for Korean Medicine, Pusan National University, Yangsan, Republic of Korea. |
| 期刊 | Journal of oral rehabilitation |
| SCI 分区 | Q1 |
| IF | 3.8 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
背景： 序贯四通道神经肌肉电刺激（NMES）最初被开发用于模拟吞咽相关肌肉的生理性激活顺序；然而，其在老年肌少症性吞咽障碍患者中的疗效仍不明确。本研究探讨了序贯四通道NMES对老年肌少症性吞咽障碍患者舌骨运动、吞咽安全性和经口摄食的影响。
方法： 四十名老年肌少症性吞咽障碍患者被随机分配到序贯四通道（n=20）或传统两通道（n=20）NMES组。两组均接受NMES干预，每次30分钟，每周五次，持续6周。结局指标包括使用视频荧光吞咽造影检查（VFSS）评估的舌骨前运动和上运动、渗透-误吸量表（PAS）以及功能性经口摄食量表（FOIS）。采用双因素重复测量方差分析评估组×时间交互效应。
结果： 在舌骨前运动（F=18.46，p<0.001，η2p=0.327）、舌骨上运动（F=6.94，p=0.012，η2p=0.154）、PAS（F=7.96，p=0.008，η2p=0.173）和FOIS（F=8.66，p=0.006，η2p=0.186）方面观察到显著的组×时间交互效应。总体而言，四通道NMES组在舌骨运动、吞咽安全性和经口摄食功能方面表现出比两通道NMES组更大的改善。
结论： 这些发现支持使用生理性序贯刺激作为一种有前景的康复策略，以解决与肌少症性吞咽障碍相关的吞咽损害。
英文摘要
BACKGROUND: Sequential 4-channel neuromuscular electrical stimulation (NMES) was originally developed to mimic the physiological activation sequence of the swallowing-related muscles; however, its efficacy in older adults with sarcopenic dysphagia remains unclear. This study investigated the effects of sequential 4-channel NMES on hyoid excursion, swallowing safety, and oral intake in older adults with sarcopenic dysphagia.
METHODS: Forty older adults with sarcopenic dysphagia were randomly assigned to either the sequential 4-channel (n = 20) or the conventional 2-channel (n = 20) NMES groups. Both groups received NMES intervention for 30 min per session, five times per week, for 6 weeks. Outcome measures included anterior and superior hyoid excursion assessed using the videofluoroscopic swallowing study (VFSS), penetration-aspiration scale (PAS), and functional oral intake scale (FOIS). Two-way repeated-measures analysis of variance was conducted to evaluate group × time interaction effects.
RESULTS: Significant group × time interaction effects were observed for anterior hyoid excursion (F = 18.46, p < 0.001, η2p = 0.327), superior hyoid excursion (F = 6.94, p = 0.012, η2p = 0.154), PAS (F = 7.96, p = 0.008, η2p = 0.173), and FOIS (F = 8.66, p = 0.006, η2p = 0.186). Overall, the 4-channel NMES group demonstrated greater improvements in hyoid excursion, swallowing safety, and oral intake function than the 2-channel NMES group.
CONCLUSION: These findings support the use of physiologically-sequenced stimulation as a promising rehabilitation strategy to address swallowing impairments associated with sarcopenic dysphagia.