前庭性偏头痛患者的认知功能：与单纯偏头痛患者有何差异？

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中文摘要

背景： 前庭系统对认知过程有重要贡献。本研究旨在检测前庭性偏头痛（VM）患者与单纯偏头痛（MO）患者在认知功能上可能存在的差异。方法：这是一项横断面研究。参与者在同一时段接受了一系列测试：简易精神状态检查（MMSE）、Stroop测验（ST）、数字广度测验（DST）、Oktem词语记忆过程测验（OVMPT）、词语和非词语划消测验、Benton线段方向判断测验（BJLOT）、Rey-Osterrieth复杂图形测验（ROCFT）、词语流畅性测验（VFT）和连线测验（TMT），此外还有贝克焦虑量表（BAI）和贝克抑郁量表（BDI）。结果：共有97名参与者（VM=34，MO=31，HC=32），在年龄、性别和教育程度上匹配。两个患者组的BAI评分均高于对照组（p<0.001）。VM患者和MO患者在Stroop任务、DSFT和DSBT上的表现均差于健康对照（所有任务p<0.05，MO组的Stroop任务3除外），但VM组与MO组之间未观察到显著差异（p>0.05）。在多变量分析中，VM患者的Stroop表现仍显著较差，而MO患者的DSFT和DSBT表现仍显著较差（p<0.05）。此外，与对照组相比，两个患者组在TMT-B上的表现均显著较差（p<0.05）。结论：总之，我们的研究表明，VM患者的注意力、工作记忆和空间认知功能受到影响。然而，VM患者与MO患者之间未发现总体认知差异。

英文摘要

BackgroundThe vestibular system contributes significantly to cognitive processes. Our study aims to detect the possible differences in cognitive function between patients with vestibular migraine (VM) and patients with migraine headaches only (MO).MethodsThis was a cross-sectional study. The participants took a number of tests during the same session: Mini Mental State Examination (MMSE), Stroop Test (ST), Digit Span Test (DST), Oktem Verbal Memory Process Test (OVMPT), Verbal and Nonverbal Cancellation Tests, Benton's Judgment Of Line Orientation Test (BJLOT), Rey-Osterrieth Complex Figure Test (ROCFT), Verbal Fluency Test (VFT), and Trail Making Test (TMT), in addition to Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI).ResultsThere were 97 participants (VM = 34, MO = 31, HC = 32), matched for age, sex, and education. Both patient groups had higher BAI scores than controls (p < 0.001). Both patients with VM and patients with MO performed worse than healthy controls on the Stroop tasks, DSFT, and DSBT (p < 0.05 for all tasks, except Stroop Task 3 in the MO group), but no significant differences were observed between the VM and MO groups (p > 0.05). In the multivariable analyses, Stroop performance remained significantly worse in patients with VM, while DSFT and DSBT performance remained significantly worse in patients with MO (p < 0.05). In addition, both patient groups showed significantly worse performance on the TMT-B compared with controls (p < 0.05).ConclusionIn conclusion, our study showed that attention, working memory, and spatial cognitive functions were affected in patients with VM. However, no overall cognitive differences were identified between patients with VM and patients with MO.