慢性头晕患者中眩晕症状量表简表的结构效度和反应性

文献信息

中文摘要

背景： 眩晕症状量表简表（VSS-SF）常用于临床前庭研究，但其作为结局指标的能力尚未被研究。
目的： 在慢性头晕个体中检验总量表以及自主神经-焦虑（VSS-A）和眩晕-失衡（VSS-V）子量表的结构效度和反应性。
方法： 采用横断面和纵向设计。预先定义了关于VSS-SF、VSS-V和VSS-A的得分与变化得分之间关系的假设，评估感知的头晕症状，以及其他评估类似构念的仪器的相应得分，要求75%的假设得到确认。还检验了变化得分区分感知改善与未改善的能力。
主要发现： VSS-SF显示出令人满意的结构效度，75%的假设得到确认，但反应性不足，仅67%的假设得到确认。只有VSS-V显示出足够的反应性，ROC曲线下面积=0.72。在0-32分量表上，区分改善与未改善患者的最佳截断值为4.5。
结论： VSS-SF及其子量表显示出可接受的结构效度，支持其临床使用。在得出结论认为它们能作为结局指标之前，需要更多关于反应性的研究。

英文摘要

BackgroundThe Vertigo Symptom Scale-Short Form (VSS-SF) is commonly used in clinical vestibular research but its ability to serve as an outcome measure has not been investigated.ObjectivesTo examine construct validity and responsiveness of the total scale and subscales addressing autonomic-anxiety (VSS-A) and vertigo-imbalance (VSS-V) in individuals with chronic dizziness.MethodsCross-sectional and longitudinal designs were applied. Predefined hypotheses were defined about the relationship between scores and change scores of the VSS-SF, VSS-V and VSS-A, assessing perceived symptoms of dizziness, and respective scores of other instruments assessing similar constructs, requiring 75% of hypothesis confirmed. The ability to discriminate between perceived improvement and not improvement by change scores was also examined.Major findingsThe VSS-SF demonstrated satisfactory construct validity with 75% of hypotheses confirmed, but not sufficient responsiveness with only 67% of hypotheses confirmed. Only the VSS-V showed adequate responsiveness to change by area under the ROC curve= 0.72. The optimal cut-off value to classify between improved and not improved patients was 4.5 on the 0-32-point scale.ConclusionsThe VSS-SF and subscales demonstrated acceptable construct validity supporting its clinical use. More studies on responsiveness are needed before a conclusion can be drawn regarding their ability to serve as an outcome measure.