计算机断层扫描测量的腹部皮下脂肪厚度与阻塞性睡眠呼吸暂停风险：一项横断面观察性研究
Computed Tomography-Measured Abdominal Subcutaneous Fat Thickness and Obstructive Sleep Apnea Risk: A Cross-Sectional Observational Study.
文献信息
| PMID | 42799626 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Bilge Aslan |
| 作者单位 | Department of Anesthesiology and Reanimation, Bilkent City Hospital, University of Health Sciences; drbilgeaslan@hotmail.com. |
| 期刊 | Journal of visualized experiments : JoVE |
| SCI 分区 | Q3 |
| IF | 1.4 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
本研究探讨了在因临床指征而获得的腹部计算机断层扫描（CT）图像上机会性测量的脐部皮下脂肪厚度（USFT）是否与使用STOP-BANG问卷评估的围手术期阻塞性睡眠呼吸暂停（OSA）风险相关。在这项横断面观察性研究中，64名成年参与者完成了STOP-BANG问卷，并使用标准化方案在现有腹部CT图像上测量了USFT。USFT与连续变量之间的关联使用Spearman相关进行评估，而STOP-BANG风险类别之间的比较使用Kruskal-Wallis检验进行。在调整年龄后，使用探索性逻辑回归评估USFT与高STOP-BANG风险之间的关联。未观察到USFT与STOP-BANG评分之间存在显著相关性（ρ = 0.142，p = 0.264），并且USFT在STOP-BANG风险类别之间没有显著差异（p = 0.677）。在报告打鼾的参与者中，USFT显著更高（p = 0.026），并且与体重指数（BMI；ρ = 0.663，p < 0.001）和颈围（ρ = 0.544，p < 0.001）呈正相关。在调整年龄后，USFT与高STOP-BANG风险没有显著关联。总体而言，在本研究中，CT测量的USFT与基于STOP-BANG的OSA风险无关。需要更大规模的研究，纳入多导睡眠图（PSG）确诊的OSA并进行充分把握度的多变量分析，以确定CT衍生的肥胖测量指标在围手术期OSA风险评估中的潜在作用。
英文摘要
This study investigated whether umbilical subcutaneous fat thickness (USFT), measured opportunistically on abdominal computed tomography (CT) images obtained for clinical indications, was associated with perioperative obstructive sleep apnea (OSA) risk assessed using the STOP-BANG questionnaire. In this cross-sectional observational study, 64 adult participants completed the STOP-BANG questionnaire, and USFT was measured on existing abdominal CT images using a standardized protocol. Associations between USFT and continuous variables were assessed using Spearman correlation, while comparisons across STOP-BANG risk categories were performed using the Kruskal-Wallis test. Exploratory logistic regression was used to assess the association between USFT and high STOP-BANG risk after adjustment for age. No significant correlation was observed between USFT and STOP-BANG score (ρ = 0.142, p = 0.264), and USFT did not differ significantly across STOP-BANG risk categories (p = 0.677). USFT was significantly higher among participants reporting snoring (p = 0.026) and showed positive correlations with body mass index (BMI; ρ = 0.663, p < 0.001) and neck circumference (ρ = 0.544, p < 0.001). USFT was not significantly associated with high STOP-BANG risk after adjustment for age. Overall, CT-measured USFT was not associated with STOP-BANG-based OSA risk in this study. Larger studies incorporating polysomnography (PSG)-confirmed OSA and adequately powered multivariable analyses are needed to determine the potential role of CT-derived adiposity measures in perioperative OSA risk assessment.