辐照聚乳糖910（Vicryl Rapide）用于鼻内黏膜闭合：缝线快速清除且无伤口并发症。

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中文摘要

背景： 鼻侧壁和鼻中隔上的标准Vicryl缝线半衰期分别为70天和64天，会导致结痂、堵塞、刺激和异味。辐照Vicryl Rapide吸收更快。
目的： 我们旨在通过评估伤口状态和缝线清除情况，评价Vicryl Rapide用于鼻腔黏膜缝合的临床实用性。
方法： 这项回顾性研究纳入了2025年10月至2026年3月期间连续接受鼻中隔成形术和/或下鼻甲切除术和/或内镜下改良内侧上颌骨切除术（EMMM）并使用Vicryl Rapide进行黏膜闭合的36例患者。缝线清除定义为鼻内镜下临床未见可见缝线材料。在门诊随访时记录伤口感染和裂开。每次随访时计数残留缝线。
结果： 未观察到伤口感染或裂开。模型估计的中位缝线清除时间在鼻中隔为15.4天（95% CI：14.2-16.6），在鼻侧壁为14.6天（95% CI：13.6-15.5），两个部位之间无显著差异（p = 0.093）。观察到的缝线最长持续时间为鼻中隔19天，鼻侧壁21天。
结论与意义： 在本系列中，Vicryl Rapide实现了短期黏膜闭合，未观察到感染或裂开。

英文摘要

BACKGROUND: Standard Vicryl sutures on the lateral nasal wall and septum show half-lives of 70 and 64 days, causing crusting, obstruction, irritation, and odor. Irradiated Vicryl Rapide absorbs faster.
AIMS: We aimed to evaluate the clinical usefulness of Vicryl Rapide for mucosal suturing in the nasal cavity by assessing wound status and suture clearance.
METHODS: This retrospective study included 36 consecutive patients who underwent septoplasty, and/or inferior turbinectomy, and/or endoscopic modified medial maxillectomy (EMMM) with Vicryl Rapide mucosal closure between October 2025 and March 2026. Suture clearance was defined as the clinical absence of visible suture material on nasal endoscopy. Wound infection and dehiscence were recorded at outpatient visits. Remaining suture threads were counted at each visit.
RESULTS: No wound infection or dehiscence was observed. Model-estimated median suture clearance time was 15.4 days (95% CI: 14.2-16.6) on the nasal septum and 14.6 days (95% CI: 13.6-15.5) on the lateral nasal wall, with no significant difference between sites (p = 0.093). The maximum observed suture persistence was 19 days on the nasal septum and 21 days on the lateral nasal wall.
CONCLUSIONS AND SIGNIFICANCE: Vicryl Rapide achieved short-term mucosal closure without observed infection or dehiscence in this series.