单纯打鼾者的鼻腔尺寸与咽气道空间：一项基于CT的横断面研究
Nasal Cavity Dimensions and Pharyngeal Airway Space in Simple Snoring: A Cross-Sectional CT-Based Study.
文献信息
| PMID | 42796404 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Jeong-Whun Kim |
| 作者单位 | Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam 13620, Republic of Korea. |
| 期刊 | Medicina (Kaunas, Lithuania) |
| SCI 分区 | Q1 |
| IF | 3 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 鼻科 |
中文摘要
背景与目的： 单纯打鼾者鼻腔尺寸与咽气道空间（PAS）之间的解剖学关系仍不明确。我们使用计算机断层扫描（CT）研究单纯打鼾成人中鼻腔尺寸与PAS之间的关联，重点关注解剖学相关性。
材料与方法： 这项横断面研究纳入83名单纯打鼾并伴有鼻塞的成人，其呼吸暂停低通气指数（AHI）< 2已确认，纳入时间为2007年至2022年。进行多导睡眠监测和CT以测量鼻腔和咽气道尺寸。在清醒CT图像上测量三个鼻腔节段的最小横截面积（mCSA）以及咽气道尺寸。采用多变量线性回归，校正年龄、性别和BMI，以评估鼻腔与咽气道尺寸之间的关联。
结果： 在校正年龄、性别和BMI后，较大的双侧最窄鼻腔横截面积与全队列中较大的PAS mCSA显著相关（标准化β = 0.26，p = 0.012）。鼻腔面积每增大10 mm2，对应PAS mCSA增大3.6%（95% CI，0.8-6.5%），该模型解释了方差的一小部分（校正R2 = 0.17）。该关联不因性别而异（交互作用p = 0.25），表明没有效应修饰的证据。
结论： 在单纯打鼾个体中，较小的鼻腔尺寸与静态CT成像上较窄的PAS相关，尽管这种关联较微弱，且仅能解释咽部口径变异的一小部分。这些发现反映了解剖学关联，不应被解释为功能性气道塌陷或疾病进展的证据。
英文摘要
Background and Objectives: The anatomical relationship between nasal cavity dimensions and the pharyngeal airway space (PAS) in simple snoring remains poorly defined. We investigated the association between nasal cavity dimensions and the PAS in adults with simple snoring using computed tomography (CT), focusing on anatomical correlations. Materials and Methods: This cross-sectional study included 83 adults with simple snoring and nasal obstruction and a confirmed apnea-hypopnea index (AHI) < 2, enrolled between 2007 and 2022. Polysomnography and CT were performed to measure nasal and pharyngeal airway dimensions. The minimum cross-sectional areas (mCSAs) of three nasal cavity segments and pharyngeal airway dimensions were measured on awake CT images. Multivariable linear regression, adjusted for age, sex, and BMI, was used to evaluate the association between the nasal and pharyngeal airway dimensions. Results: A larger bilateral narrowest nasal cross-sectional area was significantly associated with a larger PAS mCSA in the full cohort (standardized β = 0.26, p = 0.012), after adjustment for age, sex, and BMI. A 10-mm2 larger nasal area corresponded to a 3.6% larger PAS mCSA (95% CI, 0.8-6.5%), and the model explained a modest share of the variance (adjusted R2 = 0.17). The association did not differ by sex (interaction p = 0.25), indicating no evidence of effect modification. Conclusions: In individuals with simple snoring, smaller nasal cavity dimensions were associated with a narrower PAS on static CT imaging, although this association was modest and explained only a small fraction of the variation in pharyngeal calibre. These findings reflect anatomical associations and should not be interpreted as evidence of functional airway collapse or disease progression.