抑郁和焦虑与鼻中隔成形术联合下鼻甲成形术后并发症的关联
Association of Depression and Anxiety With Postoperative Complications After Septoplasty With Turbinoplasty.
文献信息
| PMID | 42788780 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Amala Nayak |
| 作者单位 | Department of Otolaryngology-Head and Neck Surgery, Virginia Commonwealth University School of Medicine, Richmond, USA. |
| 期刊 | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery |
| SCI 分区 | Q1 |
| IF | 2.9 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 鼻科 |
中文摘要
目的： 评估共病抑郁和焦虑与鼻中隔成形术联合下鼻甲成形术后并发症之间的关联，并评估治疗这些疾病是否影响手术结局。
研究设计： 采用倾向性评分匹配分析的回顾性队列研究。
地点： 利用TriNetX研究网络的多机构数据库研究。
方法： 利用TriNetX研究网络识别接受鼻中隔成形术并同期行下鼻甲成形术的患者；在调整人口统计学特征和医学共病后，进行倾向性评分匹配分析。比较无抑郁或焦虑的患者、未治疗抑郁/焦虑的患者以及接受药物治疗抑郁/焦虑的患者之间，嗅觉丧失、鼻出血、阿片类药物处方、急诊科就诊、鼻窦炎、再入院和鼻中隔穿孔的术后并发症发生率。
结果： 无抑郁或焦虑的患者（每组n=5012）相比有抑郁/焦虑的患者，鼻出血（OR 0.70，P=.0083）、鼻窦炎（OR 0.62，P=.0019）、急诊科就诊（OR 0.52，P<.0001）、医院再入院（OR 0.55，P<.0001）和术后阿片类药物处方（OR 0.77，P<.0001）的比值比较低。未治疗抑郁/焦虑的患者（每组n=4470）相比接受治疗的抑郁/焦虑患者，鼻出血的比值比较高（OR 3.94，P<.0001），但90天医院再入院风险较低（OR 0.38，P<.0001），阿片类药物处方也较低（OR 0.69，P<.0001）。
结论： 共病抑郁或焦虑与鼻中隔成形术联合下鼻甲成形术后的结局差异相关。未来需要研究来阐明治疗精神疾病对耳鼻喉科手术后结局的影响。
英文摘要
OBJECTIVES: Evaluate the association between comorbid depression and anxiety and postoperative complications following septoplasty with turbinoplasty, and assess whether treatment of these conditions influences surgical outcomes.
STUDY DESIGN: Retrospective cohort study with propensity-score matched analysis.
SETTING: Multi-institutional database study utilizing the TriNetX Research Network.
METHODS: The TriNetX Research Network was utilized to identify patients undergoing septoplasty and concurrent turbinoplasty; propensity score-matched analyses were conducted after adjusting for demographics and medical comorbidities. Postoperative complication rates for anosmia, epistaxis, opioid prescription, emergency department (ED) visits, sinusitis, readmission, and septal perforation were compared among patients without depression or anxiety, patients with untreated depression/anxiety, and patients with medication-treated depression/anxiety.
RESULTS: Patients (n = 5012 per group) without depression or anxiety had lower odds of epistaxis (OR 0.70, P = .0083), sinusitis (OR 0.62, P = .0019), ED visits (OR 0.52, P < .0001), hospital readmission (OR 0.55, P < .0001), and postoperative opioid prescription (OR 0.77, P < .0001) than patients with depression/anxiety. Patients (n = 4470 per group) with untreated depression/anxiety had higher odds of epistaxis (OR 3.94, P < .0001) but a lower 90-day risk of hospital readmission (OR 0.38, P < .0001) and opioid prescription (OR 0.69, P < .0001) compared to treated depression/anxiety.
CONCLUSION: Comorbid depression or anxiety are associated with differences in outcomes following septoplasty with turbinoplasty. Future studies are needed to clarify the impact of treating psychiatric disorders on postoperative outcomes following otolaryngology procedures.