多功能羧甲基纤维素基pH响应水凝胶：具有稳健的机械强度、粘附性和自愈合性，用于运动监测和触摸屏交互
Versatile carboxymethyl cellulose-based pH responsive hydrogel with robust mechanical strength, adhesion, and self-healing for motion monitoring and touchscreen interaction.
文献信息
| PMID | 42785888 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Durgesh Kumar Sinha |
| 作者单位 | Department of Chemistry, Indian Institute of Technology Bhilai, Durg 491001, Chhattisgarh, India. |
| 期刊 | Carbohydrate polymers |
| SCI 分区 | Q1 |
| IF | 12.4 |
| 研究类型 | 基础研究 · 基础／转化 |
| 所属专科 | 咽喉科 |
中文摘要
具有机械强度、自愈合能力、强粘附性和可靠传感性能等功能特性的水凝胶仍然是可穿戴电子设备面临的重大挑战。在此，通过紫外诱导聚合和超分子交联，由羧甲基纤维素（CMC）、聚乙烯醇（PVA）、丙烯酸（AA）和单宁酸（TA）制备了一种可持续的生物质衍生CPAT水凝胶。聚乙二醇二丙烯酸酯交联的聚丙烯酸（PAA-PEGDA）网络与动态氢键相互作用的协同整合产生了稳健的多网络结构。该材料表现出良好的拉伸性、高拉伸强度和韧性。此外，该水凝胶表现出高效的自愈合能力，愈合效率超过90%，弹性恢复率约为90%，在反复变形循环后应力保持率为96%。该水凝胶显示出强的通用粘附性、显著的pH响应性溶胀和传感行为。电化学阻抗谱显示离子电导率为3.33 × 10^-2 S cm^-1，同时在1000次加载-卸载循环中保持稳定的传感性能。该水凝胶能够实时监测人体运动和良好的生理活动，包括吞咽和与言语相关的喉部运动。该材料表现出优异的细胞相容性，维持L929成纤维细胞约93%的活力。这些结果表明CPAT水凝胶作为可穿戴传感器、人机界面和智能医疗应用的多功能平台的潜在用途。
英文摘要
Hydrogels exhibiting functional properties like mechanical strength, self-healing ability, strong adhesion, and reliable sensing performance remains a major challenge for wearable electronics. Herein, a sustainable biomass-derived CPAT hydrogel was fabricated from carboxymethyl cellulose (CMC), poly(vinyl alcohol) (PVA), acrylic acid (AA), and tannic acid (TA) through UV-induced polymerization and supramolecular crosslinking. The cooperative integration of a poly(ethylene glycol)diacrylate crosslinked poly(acrylic acid) (PAA-PEGDA) network with dynamic hydrogen-bonding interactions generated a robust multi-network architecture. This material exhibited good stretchability, high tensile strength, and toughness. Furthermore, the hydrogel demonstrated efficient self-healing with a healing efficiency exceeding 90%, an elastic recovery of approximately 90%, and 96% stress retention after repeated deformation cycles. The hydrogel displayed strong universal adhesion, pronounced pH-responsive swelling and sensing behaviour. Electrochemical impedance spectroscopy revealed an ionic conductivity of 3.33 × 10--2 S cm-1, while stable sensing performance was maintained over 1000 loading-unloading cycles. The hydrogel enabled real-time monitoring of human motions and good physiological activities, including swallowing and speech-related throat movements. The material exhibited excellent cytocompatibility, maintaining approximately 93% viability of L929 fibroblast cells. These results show the potential use of CPAT hydrogel as a multifunctional platform for wearable sensors, human-machine interfaces, and intelligent healthcare application.