喉切除术患者的生活质量与决策后悔研究

文献信息

中文摘要

全喉切除术是晚期喉癌的一种外科手术，可能影响言语、吞咽和呼吸。本研究比较了接受原发性全喉切除术联合辅助放疗（第1组）与挽救性喉切除术（第2组）患者的生活质量、吞咽功能和决策后悔。25例第1组患者和27例第2组患者完成了调查。生活质量和吞咽能力分别采用华盛顿大学生活质量问卷（UW-QOL）和M.D. Anderson吞咽困难量表（MDADI）进行评估，决策后悔采用决策后悔量表测量。第1组患者报告的平均UW-QOL总分（74.4）高于第2组（68.2）。同样，第1组患者表现出更好的吞咽结果，平均MDADI评分为70.28，而第2组为63.90。第1组患者的决策后悔评分（31.4）低于第2组（35.37），表明对治疗决策的后悔较少。然而，所有这些差异均未达到统计学显著性。总体而言，这些发现强调了充分告知患者手术对生活质量影响的重要性，以帮助他们做出决策。未来的研究可以招募更大的队列，并探讨其他喉切除术治疗/手术的有效性。

英文摘要

Total laryngectomy is a surgical procedure for advanced laryngeal cancer and can affect speech, swallowing, and breathing. This study compared the quality of life, swallowing function, and decision regret among patients who underwent primary total laryngectomy with adjuvant radiation (Group 1) versus salvage laryngectomy (Group 2). A survey was completed by 25 Group 1 patients and 27 Group 2 patients. Quality of life and swallowing ability were assessed using the University of Washington Quality of Life Questionnaire (UW-QOL) and M.D. Anderson Dysphagia Inventory (MDADI), while decision regret was measured using the Decision Regret Scale. Group 1 patients reported a higher mean total UW-QOL score (74.4) than Group 2 (68.2). Similarly, Group 1 patients demonstrated better swallowing outcomes, with a mean MDADI score of 70.28 compared to 63.90 in Group 2. Decision Regret scores were lower in Group 1 patients (31.4) than in Group 2 (35.37), indicating less regret regarding treatment decisions. However, all these differences did not reach statistical significance. Overall, these findings highlight the importance of fully informing patients of the impact of surgery on quality of life to assist them in their decision-making. Future studies can recruit larger cohorts and investigate the effectiveness of other laryngectomy treatments/procedures.