球囊扩张干预治疗卒中后环咽失弛缓症疗效的Meta分析
A meta-analysis of the efficacy of balloon dilation intervention for patients with cricopharyngeal achalasia after stroke.
文献信息
| PMID | 42780724 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Lingyun Wu |
| 作者单位 | School of Medical Sciences, Quzhou College of Technology, Quzhou, China. |
| 期刊 | Frontiers in neurology |
| SCI 分区 | Q2 |
| IF | 3.5 |
| 研究类型 | 综述 Meta · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
背景： 本研究旨在评估球囊扩张治疗卒中后吞咽障碍的疗效和安全性。
方法： 检索PubMed、Embase、Cochrane图书馆、Web of Science、中国知网（CNKI）、维普和中国万方数据库，检索时间从建库至2024年10月30日。两位作者独立筛选所有研究、提取数据并评估纳入研究的偏倚风险。使用Review Manager 5.4和Stata软件（版本16）评估研究质量。
结果： 本分析共纳入25项研究，涉及1,134例患者。结果表明，球囊扩张显著提高了有效率（OR=6.11；95% CI：4.16，8.98）、视频荧光吞咽研究（VFSS）评分（MD=2.23，95% CI：1.98，2.48）和功能性经口摄食量表（FOIS）评分（MD=1.93，95% CI：1.40，2.47）；它还缩短了吞咽通过时间（MD=-0.07；95% CI：-0.08，-0.06），改善了洼田饮水试验（KDWT）评分（MD=-1.01，95% CI：-1.55，-0.47），并降低了吸入性肺炎的发生率（OR=0.46；95% CI：0.21，0.98）。
结论： 与常规康复训练相比，球囊扩张是一种更安全、更有效改善吞咽功能的方法。
英文摘要
BACKGROUND: The present study aimed to evaluate the efficacy and safety of balloon dilatation for the treatment of swallowing disorders after stroke.
METHODS: PubMed, Embase, the Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), VIP, and the Chinese Wanfang database were searched from their inception to 30 October 2024. Two authors independently screened all studies, extracted data, and evaluated the risk of bias in the included studies. Review Manager 5.4 and Stata software (version 16) were used to assess study quality.
RESULTS: A total of 25 studies involving 1,134 patients were included in the present analysis. The results suggest that balloon dilatation significantly improves the effective rate (OR = 6.11; 95% CI: 4.16, 8.98), videofluoroscopic swallowing study (VFSS) score (MD = 2.23, 95% CI: 1.98, 2.48), and Functional Oral Intake Scale (FOIS) score (MD = 1.93, 95% CI: 1.40, 2.47); it also shortens swallowing passage time (MD = -0.07; 95% CI: -0.08, -0.06), improves the Kubota Drinking Water Test (KDWT) score (MD = -1.01, 95% CI: -1.55, -0.47), and reduces the incidence of aspiration pneumonia (OR = 0.46; 95% CI: 0.21, 0.98).
CONCLUSION: Compared to routine rehabilitation training, balloon dilation is a safer and more effective method for improving swallowing function.