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聆听疲劳对成人人工耳蜗候选者听力相关生活质量的影响

Listening Fatigue Contributes to Hearing-Related Quality of Life in Adult Cochlear Implant Candidates.

临床研究耳科IF 1.9Q2

文献信息

中文摘要

目的: 识别独立影响成人人工耳蜗(CI)候选者术前听力相关生活质量(HRQOL)的因素。
研究设计: 回顾性横断面分析。
地点: 三级学术医疗中心。
患者: 2018年至2024年间共171名接受CI候选资格评估的成人。
主要结局指标: 人工耳蜗生活质量-10总体(CIQOL Global)评分作为主要结局指标。自变量包括10项范德堡疲劳量表(VFS-A-10)、耳鸣障碍量表(THI)、年龄、耳聋持续时间以及术前安静环境下AzBio句子识别(AzBioQ)评分。
结果: 双变量分析显示,CIQOL Global评分与VFS-A-10(r=-0.56,P<0.001)及THI(r=-0.31,P=0.005)均存在显著相关性。CIQOL Global与年龄、耳聋持续时间或AzBioQ表现之间未发现显著相关性。在多变量线性回归(n=67)中,VFS-A-10是术前CIQOL Global的唯一独立预测因子(β=-0.55,P<0.001)。THI、年龄、耳聋持续时间和AzBioQ表现未提供额外的解释价值。在更大样本的成人CI候选者(n=144)中进行的敏感性分析证实了这些发现。
结论: 聆听疲劳是与CI候选者术前HRQOL相关的主要独立因素,而传统听力学指标和感知耳鸣并未独立贡献。这些发现强调了在CI候选资格评估中评估聆听疲劳的重要性,并提示针对疲劳管理的干预可能改善患者福祉。常规评估聆听疲劳有助于实现更个性化的咨询,并识别可能从更早干预中获益的CI候选者。

英文摘要

OBJECTIVE: To identify factors independently contributing to preoperative hearing-related quality of life (HRQOL) in adult cochlear implant (CI) candidates.
STUDY DESIGN: Retrospective cross-sectional analysis.
SETTING: Tertiary academic medical center.
PATIENTS: A total of 171 adults were evaluated for CI candidacy from 2018 to 2024.
MAIN OUTCOME MEASURES: Cochlear Implant Quality of Life-10 Global (CIQOL Global) scores served as the main outcome measure. Independent variables included the 10-item Vanderbilt Fatigue Scale (VFS-A-10), Tinnitus Handicap Inventory (THI), age, duration of deafness, and preoperative AzBio sentence recognition in quiet (AzBioQ) scores.
RESULTS: Bivariate analyses revealed significant correlations between CIQOL Global scores and both VFS-A-10 (r=-0.56, P<0.001) and THI (r=-0.31, P=0.005). No significant correlations were found between CIQOL Global and age, duration of deafness, or AzBioQ performance. In multivariable linear regression (n=67), VFS-A-10 was the sole independent predictor of preoperative CIQOL Global (β=-0.55, P<0.001). THI, age, duration of deafness, and AzBioQ performance did not contribute additional explanatory value. Sensitivity analysis in a larger sample of adult CI candidates (n=144) confirmed these findings.
CONCLUSIONS: Listening fatigue was the primary independent factor associated with preoperative HRQOL among CI candidates, whereas traditional audiologic measures and perceived tinnitus did not contribute independently. These findings highlight the importance of assessing listening fatigue as part of CI candidacy evaluation and suggest that interventions targeting fatigue management may improve patient well-being. Routine assessment of listening fatigue could enable more personalized counseling and identify CI candidates who might benefit from earlier intervention.