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儿童家长报告打鼾与多导睡眠图检查结果之间的年龄依赖性关联

Age-dependent association between parent-reported snoring and polysomnography findings in children.

临床研究鼻科IF 4.5Q1

文献信息

中文摘要

目的: 儿童睡眠呼吸障碍(SDB)风险的初步识别通常依赖于家长报告的症状,尤其是打鼾。本研究旨在评估年龄如何影响家长报告打鼾与多导睡眠图(PSG)上SDB相关发现之间的关联。我们假设,在年龄较小的儿童中,家长报告打鼾与PSG上SDB相关发现的相关性更强。
方法: 本研究是儿童睡眠项目的一部分,这是一项关于在坦佩雷大学医院出生儿童的纵向出生队列研究,于2013年至2025年间开展,包括在2岁、6岁和12岁时的临床检查,根据家长是否报告儿童打鼾对儿童进行比较。
结果: 在2岁儿童(p = 0.009)和6岁儿童(p = 0.045)中发现了家长报告打鼾与PSG诊断的阻塞性睡眠呼吸暂停(OSA)之间的关联。在2岁和6岁儿童中,家长报告打鼾对OSA显示出高敏感性(1.0)和阴性预测值(1.0),其预测性能在12岁儿童中减弱。被报告打鼾的2岁儿童比非打鼾者具有更高的呼吸努力(p = 0.022)。在6岁和12岁儿童中,被报告打鼾者比非打鼾者存在更多的气流受限。
结论: 家长报告打鼾可能是一种临床上有用的筛查工具,可与其他检查方法一起用于排除年龄较小儿童的SDB。然而,随着儿童接近青春期及在青春期期间,其可靠性似乎降低。因此,考虑SDB病理生理学的年龄相关变化以及儿童接近青春期时家长观察行为的变化非常重要。

英文摘要

PURPOSE: The initial identification of children at risk for sleep disordered breathing (SDB) commonly relies on parental reports of symptoms, particularly snoring. This study aims to assess how age affects the association between parent-reported snoring and SDB-related findings on polysomnography (PSG). We hypothesized that parent-reported snoring correlates more strongly with SDB-related findings on PSG in younger children.
METHODS: This study was part of the Child Sleep project, a longitudinal birth cohort study on children born at Tampere University Hospital, which was carried out between 2013 and 2025 and included clinical examinations at ages 2, 6, and 12 years, where children were compared based on whether their parents reported them to snore.
RESULTS: An association between parent-reported snoring and PSG-diagnosed obstructive sleep apnea (OSA) was found in children aged 2 years (p = 0.009) and 6 years (p = 0.045). Parent-reported snoring showed a high sensitivity (1.0) and negative predictive value (1.0) for OSA in both 2- and 6-year-olds, with its predictive performance diminishing in 12-year-olds. 2-year-olds who were reported to snore had higher respiratory effort than non-snorers (p = 0.022). In children aged 6 and 12 years there was more flow limitation among those reported to snore than among non-snorers.
CONCLUSION: Parent-reported snoring may be a clinically useful screening tool for excluding SDB in younger children alongside other examination methods. However, its reliability appears to decrease as children approach puberty and during puberty. Thus, it is important to consider age-related changes in the pathophysiology of SDB and changes in parental observational behavior as children approach adolescence.