COVID-19期间儿童分泌性中耳炎手术趋势:一项时间序列研究
Pediatric Otitis Media With Effusion Surgical Trends During COVID-19: A Time-Series Study.
文献信息
| PMID | 42768420 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Hiroshi Hidaka |
| 作者单位 | Department of Otorhinolaryngology-Head and Neck Surgery, Kansai Medical University, Hirakata, Japan. |
| 期刊 | The Laryngoscope |
| SCI 分区 | Q2 |
| IF | 2.3 |
| 研究类型 | 临床研究 · 临床 |
| 所属专科 | 耳科 |
中文摘要
目的: 评估COVID-19大流行对日本儿童分泌性中耳炎(OME)手术的影响,比较一般人群与高危人群(唐氏综合征和腭裂),以区分手术需求的环境驱动因素和解剖驱动因素。
方法: 这项回顾性队列研究使用了日本诊断程序组合数据库(2013年4月至2023年3月)。纳入接受鼓膜置管或鼓膜切开术的18岁以下儿童。采用中断时间序列(ITS)分析来估计即时“水平变化”和大流行期间“趋势变化”,有效考虑10年预先存在的长期趋势,以分离大流行的影响。
结果: 在22,748例手术病例中,未观察到显著的大流行前趋势(+0.05例手术/月),随后出现显著的即时水平变化(-107.55例手术/月)和非显著的斜率变化(0.95例手术/月)。相比之下,唐氏综合征组和腭裂组的即时水平变化无统计学显著性,表明手术量相对保持。同期腺样体切除术和扁桃体切除术分别从38.8%显著下降至29.7%和从23.2%下降至16.9%(p < 0.001)。
结论: 虽然一般人群的OME手术量急剧下降,可能由于社区获得性呼吸道感染减少,但在高危儿童中仍保持韧性。这些发现表明,虽然环境因素驱动一般人群的OME,但解剖脆弱性使得高危群体即使在疫情期间也需要持续的手术干预。这种区分对未来公共卫生危机中的手术优先级提供了关键框架。
英文摘要
OBJECTIVE: To evaluate the impact of the COVID-19 pandemic on pediatric surgery for otitis media with effusion (OME) in Japan, comparing the general population with high-risk groups (Down syndrome and cleft palate) to differentiate between environmental and anatomical drivers of surgical demand.
METHODS: This retrospective cohort study used the Japanese Diagnosis Procedure Combination database (April 2013 to March 2023). Children < 18 years undergoing tympanostomy tube insertion or myringotomy were included. Interrupted time-series (ITS) analysis was employed to estimate immediate "level shifts" and pandemic-period "trend changes," effectively accounting for 10-year pre-existing secular trends to isolate the pandemic's impact.
RESULTS: Among 22,748 surgical cases, no significant pre-pandemic trend (+0.05 surgeries/month) was observed, followed by a significant immediate level shift (-107.55 surgeries/month) and a non-significant slope change (0.95 surgeries/month). In contrast, immediate level shifts in the Down syndrome and cleft palate groups were not statistically significant, indicating relatively preserved surgical volume. Concomitant adenoidectomy and tonsillectomy decreased significantly from 38.8% to 29.7% and 23.2% to 16.9%, respectively (p < 0.001).
CONCLUSIONS: While OME surgical volume for the general population plummeted, likely due to reduced community-acquired respiratory infections, it remained resilient in high-risk children. These findings suggest that while environmental factors drive OME in the general population, anatomical vulnerabilities necessitate consistent surgical intervention in high-risk groups even during a pandemic. This distinction provides a crucial framework for surgical prioritization in future public health crises.