生物标志物检测阻塞性睡眠呼吸暂停的诊断准确性
Diagnostic accuracy of biological markers for detecting obstructive sleep apnoea.
文献信息
| PMID | 42765455 |
|---|---|
| 原文 | 在 PubMed 查看原文 ↗ |
| 发表日期 | 2026 |
| 作者 | Graziela De Luca Canto |
| 作者单位 | Graduate Program in Evidence-Based Health, Department of Medicine, Federal University of São Paulo, São Paulo, Brazil. |
| 期刊 | The Cochrane database of systematic reviews |
| SCI 分区 | Q1 |
| IF | 10.8 |
| 研究类型 | 综述 Meta · 临床 |
| 所属专科 | 咽喉科 |
中文摘要
这是一项Cochrane综述(诊断性)的方案。目标如下: 确定血液、唾液、尿液或呼出气冷凝液中任何类型的生物标志物在成人(>18岁)中检测阻塞性睡眠呼吸暂停(OSA)的准确性。次要目标:确定单个生物标志物单独或联合检测OSA的准确性。比较生物标志物与整夜多导睡眠监测(PSG)和家庭睡眠呼吸暂停检测(HSAT)的准确性。研究生物标志物与整夜PSG和HSAT在不同OSA严重程度(轻度、中度、重度)人群中的准确性。评估不同样本类型的生物标志物识别OSA的准确性。
英文摘要
This is a protocol for a Cochrane review (diagnostic). The objectives are as follows: To determine the accuracy of any type of biological marker found in blood, saliva, urine or breath condensation to detect obstructive sleep apnoea (OSA) in adults (> 18 years). Secondary objectives To identify the accuracy of individual biomarkers alone or in combination for detecting OSA. To find the accuracy of biological markers compared to overnight polysomnography (PSG) and home sleep apnoea test (HSAT). To investigate the accuracy of biological markers compared to overnight PSG and to HSAT in people with different degrees of severity of OSA (mild, moderate, severe). To evaluate the accuracy of biomarkers from different sample types to identify OSA.